4C5L
Structure of the pyridoxal kinase from Staphylococcus aureus in complex with pyridoxal
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0005829 | cellular_component | cytosol |
| A | 0008902 | molecular_function | hydroxymethylpyrimidine kinase activity |
| A | 0008972 | molecular_function | phosphomethylpyrimidine kinase activity |
| A | 0009228 | biological_process | thiamine biosynthetic process |
| A | 0016301 | molecular_function | kinase activity |
| A | 0016310 | biological_process | phosphorylation |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0005829 | cellular_component | cytosol |
| B | 0008902 | molecular_function | hydroxymethylpyrimidine kinase activity |
| B | 0008972 | molecular_function | phosphomethylpyrimidine kinase activity |
| B | 0009228 | biological_process | thiamine biosynthetic process |
| B | 0016301 | molecular_function | kinase activity |
| B | 0016310 | biological_process | phosphorylation |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0005829 | cellular_component | cytosol |
| C | 0008902 | molecular_function | hydroxymethylpyrimidine kinase activity |
| C | 0008972 | molecular_function | phosphomethylpyrimidine kinase activity |
| C | 0009228 | biological_process | thiamine biosynthetic process |
| C | 0016301 | molecular_function | kinase activity |
| C | 0016310 | biological_process | phosphorylation |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0005829 | cellular_component | cytosol |
| D | 0008902 | molecular_function | hydroxymethylpyrimidine kinase activity |
| D | 0008972 | molecular_function | phosphomethylpyrimidine kinase activity |
| D | 0009228 | biological_process | thiamine biosynthetic process |
| D | 0016301 | molecular_function | kinase activity |
| D | 0016310 | biological_process | phosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE UEG A 300 |
| Chain | Residue |
| A | GLY11 |
| A | HOH2009 |
| A | HOH2030 |
| A | SER12 |
| A | ASP13 |
| A | GLY19 |
| A | VAL42 |
| A | CYS110 |
| A | LYS111 |
| A | HIS210 |
| A | CYS214 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PXL B 300 |
| Chain | Residue |
| B | GLY11 |
| B | SER12 |
| B | ASP13 |
| B | GLY19 |
| B | VAL42 |
| B | CYS214 |
| B | HOH2003 |
| site_id | AC3 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE UEG C 300 |
| Chain | Residue |
| C | GLY11 |
| C | ASP13 |
| C | ALA18 |
| C | GLY19 |
| C | VAL42 |
| C | CYS110 |
| C | HIS210 |
| C | CYS214 |
| C | HOH2003 |
| C | HOH2052 |
| site_id | AC4 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE UEG D 300 |
| Chain | Residue |
| D | GLY11 |
| D | SER12 |
| D | ASP13 |
| D | ALA18 |
| D | GLY19 |
| D | VAL42 |
| D | CYS110 |
| D | HIS210 |
| D | CYS214 |
| D | HOH2007 |
| D | HOH2054 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 301 |
| Chain | Residue |
| A | LYS111 |
| A | ASN139 |
| A | LYS176 |
| A | GLY213 |
| A | HOH2056 |
| A | HOH2057 |
| A | HOH2059 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 301 |
| Chain | Residue |
| B | ASN139 |
| B | LYS176 |
| B | GLY213 |
| B | HOH2044 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 302 |
| Chain | Residue |
| A | GLY72 |
| A | ASN98 |
| A | HOH2041 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 D 301 |
| Chain | Residue |
| D | ASN139 |
| D | LYS176 |
| D | GLY213 |
