4C5K
Structure of the pyridoxal kinase from Staphylococcus aureus in complex with ADP
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005829 | cellular_component | cytosol |
| A | 0008478 | molecular_function | pyridoxal kinase activity |
| A | 0008902 | molecular_function | hydroxymethylpyrimidine kinase activity |
| A | 0008972 | molecular_function | phosphomethylpyrimidine kinase activity |
| A | 0009228 | biological_process | thiamine biosynthetic process |
| A | 0016301 | molecular_function | kinase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005829 | cellular_component | cytosol |
| B | 0008478 | molecular_function | pyridoxal kinase activity |
| B | 0008902 | molecular_function | hydroxymethylpyrimidine kinase activity |
| B | 0008972 | molecular_function | phosphomethylpyrimidine kinase activity |
| B | 0009228 | biological_process | thiamine biosynthetic process |
| B | 0016301 | molecular_function | kinase activity |
| B | 0016740 | molecular_function | transferase activity |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0005524 | molecular_function | ATP binding |
| C | 0005829 | cellular_component | cytosol |
| C | 0008478 | molecular_function | pyridoxal kinase activity |
| C | 0008902 | molecular_function | hydroxymethylpyrimidine kinase activity |
| C | 0008972 | molecular_function | phosphomethylpyrimidine kinase activity |
| C | 0009228 | biological_process | thiamine biosynthetic process |
| C | 0016301 | molecular_function | kinase activity |
| C | 0016740 | molecular_function | transferase activity |
| C | 0046872 | molecular_function | metal ion binding |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0005524 | molecular_function | ATP binding |
| D | 0005829 | cellular_component | cytosol |
| D | 0008478 | molecular_function | pyridoxal kinase activity |
| D | 0008902 | molecular_function | hydroxymethylpyrimidine kinase activity |
| D | 0008972 | molecular_function | phosphomethylpyrimidine kinase activity |
| D | 0009228 | biological_process | thiamine biosynthetic process |
| D | 0016301 | molecular_function | kinase activity |
| D | 0016740 | molecular_function | transferase activity |
| D | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE ADP A 1277 |
| Chain | Residue |
| A | LYS176 |
| A | GLN205 |
| A | ASN209 |
| A | ALA212 |
| A | GLY213 |
| A | LYS238 |
| A | ILE245 |
| A | SO41280 |
| A | HOH2150 |
| A | HOH2151 |
| A | HOH2178 |
| A | GLY178 |
| A | LYS179 |
| A | ALA180 |
| A | SER186 |
| A | ASP188 |
| A | ASP202 |
| A | MET203 |
| A | PHE204 |
| site_id | AC2 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE ADP B 1277 |
| Chain | Residue |
| B | ASN139 |
| B | LYS176 |
| B | LYS179 |
| B | SER186 |
| B | ASP188 |
| B | ASP202 |
| B | MET203 |
| B | PHE204 |
| B | GLN205 |
| B | ASN209 |
| B | GLY213 |
| B | LYS238 |
| B | ILE245 |
| B | SO41278 |
| B | HOH2130 |
| B | HOH2131 |
| B | HOH2146 |
| B | HOH2147 |
| B | HOH2173 |
| site_id | AC3 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE ADP C 1277 |
| Chain | Residue |
| C | ASN139 |
| C | LYS176 |
| C | LYS179 |
| C | SER186 |
| C | ASP188 |
| C | ASP202 |
| C | MET203 |
| C | PHE204 |
| C | GLN205 |
| C | ASN209 |
| C | ALA212 |
| C | GLY213 |
| C | LYS238 |
| C | ILE245 |
| C | SO41279 |
| C | HOH2069 |
| C | HOH2070 |
| C | HOH2107 |
| C | HOH2118 |
| site_id | AC4 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE ADP D 1277 |
| Chain | Residue |
| D | ASN139 |
| D | LYS176 |
| D | GLY178 |
| D | LYS179 |
| D | SER186 |
| D | ASP188 |
| D | ASP202 |
| D | MET203 |
| D | PHE204 |
| D | GLN205 |
| D | ASN209 |
| D | GLY213 |
| D | LYS238 |
| D | ILE245 |
| D | SO41278 |
| D | HOH2138 |
| D | HOH2165 |
| D | HOH2179 |
| D | HOH2261 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1278 |
| Chain | Residue |
| B | HIS210 |
| B | GLY211 |
| B | ALA212 |
| B | GLY213 |
| B | CYS214 |
| B | ADP1277 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1278 |
| Chain | Residue |
| A | GLY72 |
| A | ASN98 |
| A | HOH2016 |
| A | HOH2103 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1279 |
| Chain | Residue |
| A | GLN205 |
| A | GLN206 |
| A | SER207 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1279 |
| Chain | Residue |
| B | GLN205 |
| B | GLN206 |
| B | SER207 |
| B | HOH2184 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 C 1278 |
| Chain | Residue |
| A | GLU123 |
| C | GLN205 |
| C | GLN206 |
| C | SER207 |
| C | HOH2171 |
| site_id | BC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 C 1279 |
| Chain | Residue |
| C | GLY211 |
| C | ALA212 |
| C | GLY213 |
| C | CYS214 |
| C | ADP1277 |
| C | HIS210 |
| site_id | BC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1280 |
| Chain | Residue |
| A | HIS210 |
| A | GLY211 |
| A | ALA212 |
| A | GLY213 |
| A | CYS214 |
| A | ADP1277 |
| site_id | BC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 D 1278 |
| Chain | Residue |
| D | GLY211 |
| D | ALA212 |
| D | GLY213 |
| D | CYS214 |
| D | ADP1277 |
| D | HOH2207 |
| D | HOH2262 |
| site_id | BC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 D 1279 |
| Chain | Residue |
| D | GLY72 |
| D | ASN98 |
| D | HOH2008 |
| D | HOH2079 |
| D | HOH2082 |
| site_id | BC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 D 1280 |
| Chain | Residue |
| D | GLN205 |
| D | GLN206 |
| D | SER207 |
| site_id | BC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 D 1281 |
| Chain | Residue |
| D | SER229 |
| D | LYS231 |
| D | HOH2181 |
| D | HOH2182 |
| D | HOH2220 |
| site_id | BC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1280 |
| Chain | Residue |
| B | TYR208 |
| B | LYS250 |
| B | HOH2153 |
| B | HOH2154 |
| B | HOH2189 |
| B | HOH2237 |
| site_id | BC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 C 1280 |
| Chain | Residue |
| C | LYS5 |
| C | GLY72 |
| C | ASN98 |
| C | HOH2010 |
| C | HOH2047 |
