4C20
L-Fucose Isomerase
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005996 | biological_process | monosaccharide metabolic process |
| A | 0006004 | biological_process | fucose metabolic process |
| A | 0008736 | molecular_function | L-fucose isomerase activity |
| A | 0008790 | molecular_function | arabinose isomerase activity |
| A | 0016853 | molecular_function | isomerase activity |
| A | 0016861 | molecular_function | intramolecular oxidoreductase activity, interconverting aldoses and ketoses |
| A | 0019317 | biological_process | fucose catabolic process |
| A | 0019571 | biological_process | D-arabinose catabolic process |
| A | 0030145 | molecular_function | manganese ion binding |
| A | 0042355 | biological_process | L-fucose catabolic process |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005996 | biological_process | monosaccharide metabolic process |
| B | 0006004 | biological_process | fucose metabolic process |
| B | 0008736 | molecular_function | L-fucose isomerase activity |
| B | 0008790 | molecular_function | arabinose isomerase activity |
| B | 0016853 | molecular_function | isomerase activity |
| B | 0016861 | molecular_function | intramolecular oxidoreductase activity, interconverting aldoses and ketoses |
| B | 0019317 | biological_process | fucose catabolic process |
| B | 0019571 | biological_process | D-arabinose catabolic process |
| B | 0030145 | molecular_function | manganese ion binding |
| B | 0042355 | biological_process | L-fucose catabolic process |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MN A 601 |
| Chain | Residue |
| A | GLU335 |
| A | ASP359 |
| A | HIS525 |
| A | EDO1594 |
| A | HOH2259 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MN B 601 |
| Chain | Residue |
| B | HOH2250 |
| B | GLU335 |
| B | ASP359 |
| B | HIS525 |
| B | EDO1593 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 1589 |
| Chain | Residue |
| A | ARG171 |
| A | ASP172 |
| A | HIS587 |
| A | HOH2125 |
| B | PRO99 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 1590 |
| Chain | Residue |
| A | LEU119 |
| A | LEU123 |
| A | ASN519 |
| A | LYS562 |
| A | HOH2093 |
| A | HOH2346 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 1589 |
| Chain | Residue |
| B | GLU555 |
| B | THR569 |
| B | GLU570 |
| B | HOH2378 |
| B | HOH2379 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO A 1591 |
| Chain | Residue |
| A | HIS375 |
| A | THR376 |
| A | HOH2329 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO B 1590 |
| Chain | Residue |
| B | VAL236 |
| B | TRP258 |
| B | HOH2213 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 1591 |
| Chain | Residue |
| A | PRO99 |
| B | ARG171 |
| B | ASP172 |
| B | HIS587 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 1592 |
| Chain | Residue |
| A | LEU43 |
| A | LYS44 |
| A | THR351 |
| A | ASN352 |
| A | HOH2263 |
| site_id | BC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1593 |
| Chain | Residue |
| A | GLU555 |
| A | GLU570 |
| A | LEU572 |
| A | HOH2367 |
| A | HOH2368 |
| A | HOH2382 |
| site_id | BC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO B 1592 |
| Chain | Residue |
| A | ARG217 |
| B | ARG435 |
| B | ARG439 |
| site_id | BC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO B 1593 |
| Chain | Residue |
| B | TRP88 |
| B | GLU335 |
| B | ASP359 |
| B | SER391 |
| B | ASN524 |
| B | HIS525 |
| B | MN601 |
| site_id | BC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1594 |
| Chain | Residue |
| B | SER574 |
| B | TYR577 |
| B | ARG578 |
| B | ARG578 |
| site_id | BC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 1595 |
| Chain | Residue |
| B | GLU155 |
| B | ARG159 |
| B | ASP557 |
| B | HOH2345 |
| B | HOH2367 |
| site_id | BC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 1594 |
| Chain | Residue |
| A | VAL117 |
| A | MET183 |
| A | GLU335 |
| A | ASP359 |
| A | SER391 |
| A | MN601 |
| A | HOH2233 |
| site_id | BC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1596 |
| Chain | Residue |
| B | TRP231 |
| B | PHE321 |
| B | ASP322 |
| B | GLU418 |
| B | HOH2198 |
| B | HOH2288 |
| site_id | BC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1595 |
| Chain | Residue |
| A | TYR476 |
| A | ARG504 |
| A | HIS532 |
| site_id | BC9 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE TRS A 1596 |
| Chain | Residue |
| A | GLY130 |
| A | LYS464 |
| A | LEU582 |
| A | LEU583 |
| A | HOH2083 |
| A | HOH2086 |
| B | HOH2391 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | ACT_SITE: Proton acceptor => ECO:0000255|HAMAP-Rule:MF_01254 |
| Chain | Residue | Details |
| A | GLU335 | |
| A | ASP359 | |
| B | GLU335 | |
| B | ASP359 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_01254 |
| Chain | Residue | Details |
| A | GLU335 | |
| A | ASP359 | |
| A | HIS525 | |
| B | GLU335 | |
| B | ASP359 | |
| B | HIS525 |
