Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 30 |
| Details | BINDING SITE FOR RESIDUE GDS A 500 |
| Chain | Residue |
| A | VAL10 |
| A | ARG76 |
| A | VAL115 |
| A | ASN118 |
| A | THR119 |
| A | SER142 |
| A | GLU143 |
| A | ASP144 |
| A | GLN148 |
| A | LYS160 |
| A | PHE162 |
| A | THR12 |
| A | GLU163 |
| A | CD1244 |
| A | CD1254 |
| A | HOH2021 |
| A | HOH2203 |
| A | HOH2211 |
| A | HOH2238 |
| A | HOH2345 |
| A | HOH2346 |
| B | GLU50 |
| A | THR13 |
| B | GDS500 |
| A | GLU50 |
| A | TRP51 |
| A | ASN68 |
| A | ASN69 |
| A | ILE70 |
| A | SER71 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CD A 1240 |
| Chain | Residue |
| A | ASP2 |
| A | ASP43 |
| A | CL1258 |
| A | CL1259 |
| A | HOH2007 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CD A 1241 |
| Chain | Residue |
| A | ASP2 |
| A | ASP40 |
| A | CL1258 |
| A | HOH2005 |
| A | HOH2078 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CD A 1242 |
| Chain | Residue |
| A | ASP100 |
| A | HIS110 |
| A | CL1261 |
| A | HOH2181 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CD A 1243 |
| Chain | Residue |
| A | HIS147 |
| A | CL1262 |
| A | HOH2243 |
| A | HOH2247 |
| B | GLU19 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CD A 1244 |
| Chain | Residue |
| A | GLU50 |
| A | GDS500 |
| B | GLU50 |
| B | GDS500 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CD A 1245 |
| Chain | Residue |
| A | ASP144 |
| A | CL1262 |
| A | HOH2243 |
| A | HOH2244 |
| A | HOH2347 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CD A 1246 |
| Chain | Residue |
| A | GLU132 |
| A | CD1263 |
| A | HOH2178 |
| A | HOH2225 |
| A | HOH2226 |
| A | HOH2227 |
| A | HOH2355 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CD A 1247 |
| Chain | Residue |
| A | GLN47 |
| A | HOH2090 |
| A | HOH2098 |
| A | HOH2100 |
| A | HOH2101 |
| A | HOH2348 |
| A | HOH2349 |
| site_id | BC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CD A 1248 |
| Chain | Residue |
| A | ARG150 |
| A | ASP154 |
| A | HOH2250 |
| A | HOH2251 |
| A | HOH2350 |
| site_id | BC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CD A 1249 |
| Chain | Residue |
| A | ASP158 |
| A | HOH2194 |
| A | HOH2258 |
| site_id | BC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CD A 1250 |
| Chain | Residue |
| A | ASP187 |
| A | HOH2285 |
| A | HOH2286 |
| A | HOH2352 |
| site_id | BC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CD A 1251 |
| Chain | Residue |
| A | ASP202 |
| A | HOH2298 |
| site_id | BC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CD A 1252 |
| Chain | Residue |
| A | LYS48 |
| A | HOH2017 |
| A | HOH2105 |
| A | HOH2106 |
| A | HOH2346 |
| B | GLU143 |
| B | GDS500 |
| site_id | BC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CD A 1253 |
| Chain | Residue |
| A | ASN105 |
| A | HOH2187 |
| A | HOH2189 |
| B | ASP187 |
| site_id | BC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CD A 1254 |
| Chain | Residue |
| A | HOH2238 |
| A | HOH2240 |
| A | HOH2241 |
| A | HOH2345 |
| A | GLU143 |
| A | GDS500 |
| site_id | BC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CD A 1255 |
| Chain | Residue |
| A | GLU221 |
| A | HOH2319 |
| A | HOH2320 |
| site_id | BC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CD A 1256 |
| Chain | Residue |
| A | GLU216 |
| A | HOH2314 |
| A | HOH2353 |
| A | HOH2354 |
| site_id | CC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CD A 1257 |
| Chain | Residue |
| A | ASP61 |
| A | ASP199 |
| A | GLN200 |
| site_id | CC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL A 1258 |
| Chain | Residue |
| A | ASP2 |
| A | CD1240 |
| A | CD1241 |
| A | HOH2005 |
| A | HOH2077 |
| site_id | CC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL A 1259 |
| Chain | Residue |
| A | ASP43 |
| A | CD1240 |
| A | HOH2001 |
| site_id | CC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CL A 1260 |
| Chain | Residue |
| A | GLU19 |
| B | ASP144 |
| B | HIS147 |
| B | CD1242 |
| B | CD1243 |
| B | CL1253 |
| site_id | CC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 1261 |
| Chain | Residue |
| A | HIS110 |
| A | CD1242 |
| A | HOH2180 |
| A | HOH2351 |
| site_id | CC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL A 1262 |
| Chain | Residue |
| A | HIS147 |
| A | CD1243 |
| A | CD1245 |
| A | HOH2242 |
| B | GLU19 |
| site_id | CC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CD A 1263 |
| Chain | Residue |
| A | LYS97 |
| A | ASP98 |
| A | CD1246 |
| A | HOH2178 |
| A | HOH2355 |
| site_id | CC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CD A 1265 |
| Chain | Residue |
| A | GLU132 |
| A | HOH2223 |
| A | HOH2225 |
| A | HOH2356 |
| site_id | CC9 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CD A 1266 |
| Chain | Residue |
| A | HOH2150 |
| A | HOH2357 |
| site_id | DC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CD A 1267 |
| Chain | Residue |
| A | HOH2312 |
| A | HOH2358 |
| A | HOH2359 |
| site_id | DC2 |
| Number of Residues | 31 |
| Details | BINDING SITE FOR RESIDUE GDS B 500 |
| Chain | Residue |
| A | GLU50 |
| A | GDS500 |
| A | CD1244 |
| A | CD1252 |
| A | HOH2106 |
| A | HOH2111 |
| A | HOH2345 |
| A | HOH2346 |
| B | THR12 |
| B | THR13 |
| B | GLU50 |
| B | TRP51 |
| B | ASN68 |
| B | ASN69 |
| B | ILE70 |
| B | SER71 |
| B | ARG76 |
| B | VAL115 |
| B | ASN118 |
| B | THR119 |
| B | SER142 |
| B | GLU143 |
| B | ASP144 |
| B | GLN148 |
| B | LYS160 |
| B | PHE162 |
| B | GLU163 |
| B | HOH2007 |
| B | HOH2069 |
| B | HOH2170 |
| B | HOH2177 |
| site_id | DC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CD B 1241 |
| Chain | Residue |
| A | ASP235 |
| B | ASP106 |
| B | HOH2142 |
| B | HOH2150 |
| B | HOH2152 |
| site_id | DC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CD B 1242 |
| Chain | Residue |
| A | GLU19 |
| A | CL1260 |
| A | HOH2036 |
| B | HIS147 |
| B | CL1253 |
| site_id | DC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CD B 1243 |
| Chain | Residue |
| A | CL1260 |
| B | ASP144 |
| B | CL1253 |
| B | HOH2202 |
| B | HOH2204 |
| site_id | DC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CD B 1244 |
| Chain | Residue |
| B | ASP158 |
| B | HOH2162 |
| B | HOH2163 |
| B | HOH2217 |
| B | HOH2291 |
| B | HOH2292 |
| site_id | DC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CD B 1245 |
| Chain | Residue |
| B | LYS97 |
| B | HOH2131 |
| B | HOH2132 |
| B | HOH2133 |
| B | HOH2134 |
| B | HOH2293 |
| site_id | DC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CD B 1246 |
| Chain | Residue |
| A | HOH2200 |
| A | HOH2248 |
| A | HOH2249 |
| B | GLN47 |
| B | HOH2061 |
| B | HOH2294 |
| site_id | DC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CD B 1247 |
| Chain | Residue |
| B | GLU30 |
| B | HOH2032 |
| B | HOH2295 |
| site_id | EC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CD B 1248 |
| Chain | Residue |
| B | ASP199 |
| B | GLN200 |
| B | HOH2251 |
| B | HOH2254 |
| B | HOH2296 |
| site_id | EC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CD B 1249 |
| Chain | Residue |
| B | GLN135 |
| B | HOH2185 |
| B | HOH2196 |
| site_id | EC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CD B 1250 |
| Chain | Residue |
| B | ARG150 |
| B | ASP154 |
| site_id | EC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CD B 1251 |
| Chain | Residue |
| B | GLU216 |
| B | HOH2263 |
| B | HOH2285 |
| B | HOH2298 |
| site_id | EC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CD B 1252 |
| Chain | Residue |
| B | HOH2103 |
| B | HOH2104 |
| B | HOH2301 |
| site_id | EC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL B 1253 |
| Chain | Residue |
| A | CL1260 |
| B | ASP144 |
| B | HIS147 |
| B | CD1242 |
| B | CD1243 |
| site_id | EC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CD B 1254 |
| Chain | Residue |
| A | HOH2342 |
| B | ASP100 |
| B | HIS110 |
| B | CD1255 |
| B | HOH2143 |
| B | HOH2144 |
| site_id | EC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CD B 1255 |
| Chain | Residue |
| B | ASP100 |
| B | HIS110 |
| B | CD1254 |
| B | HOH2140 |
| B | HOH2144 |
| site_id | EC9 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CD B 1256 |
| site_id | FC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CD B 1257 |
| Chain | Residue |
| B | HOH2302 |
| B | HOH2303 |
| B | HOH2304 |
| B | HOH2305 |
| B | HOH2306 |
| site_id | FC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CD B 1258 |
| Chain | Residue |
| B | HOH2307 |
| B | HOH2308 |
| B | HOH2309 |
| site_id | FC3 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CD B 1259 |
