4C0Q

Transportin 3 in complex with Ran(Q69L)GTP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005515	molecular_function	protein binding
A	0005635	cellular_component	nuclear envelope
A	0005642	cellular_component	annulate lamellae
A	0005654	cellular_component	nucleoplasm
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006606	biological_process	protein import into nucleus
A	0015031	biological_process	protein transport
A	0031267	molecular_function	small GTPase binding
A	0042802	molecular_function	identical protein binding
A	0061608	molecular_function	nuclear import signal receptor activity
B	0005515	molecular_function	protein binding
B	0005635	cellular_component	nuclear envelope
B	0005642	cellular_component	annulate lamellae
B	0005654	cellular_component	nucleoplasm
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006606	biological_process	protein import into nucleus
B	0015031	biological_process	protein transport
B	0031267	molecular_function	small GTPase binding
B	0042802	molecular_function	identical protein binding
B	0061608	molecular_function	nuclear import signal receptor activity
C	0000054	biological_process	ribosomal subunit export from nucleus
C	0000055	biological_process	ribosomal large subunit export from nucleus
C	0000056	biological_process	ribosomal small subunit export from nucleus
C	0000070	biological_process	mitotic sister chromatid segregation
C	0000166	molecular_function	nucleotide binding
C	0000278	biological_process	mitotic cell cycle
C	0000287	molecular_function	magnesium ion binding
C	0000785	cellular_component	chromatin
C	0001673	cellular_component	male germ cell nucleus
C	0002177	cellular_component	manchette
C	0003682	molecular_function	chromatin binding
C	0003723	molecular_function	RNA binding
C	0003924	molecular_function	GTPase activity
C	0003925	molecular_function	G protein activity
C	0005049	molecular_function	nuclear export signal receptor activity
C	0005515	molecular_function	protein binding
C	0005525	molecular_function	GTP binding
C	0005634	cellular_component	nucleus
C	0005635	cellular_component	nuclear envelope
C	0005643	cellular_component	nuclear pore
C	0005654	cellular_component	nucleoplasm
C	0005730	cellular_component	nucleolus
C	0005737	cellular_component	cytoplasm
C	0005814	cellular_component	centriole
C	0005829	cellular_component	cytosol
C	0006259	biological_process	DNA metabolic process
C	0006606	biological_process	protein import into nucleus
C	0006611	biological_process	protein export from nucleus
C	0006913	biological_process	nucleocytoplasmic transport
C	0007052	biological_process	mitotic spindle organization
C	0007286	biological_process	spermatid development
C	0008104	biological_process	intracellular protein localization
C	0015031	biological_process	protein transport
C	0016020	cellular_component	membrane
C	0016032	biological_process	viral process
C	0016787	molecular_function	hydrolase activity
C	0019003	molecular_function	GDP binding
C	0019904	molecular_function	protein domain specific binding
C	0021766	biological_process	hippocampus development
C	0030036	biological_process	actin cytoskeleton organization
C	0030496	cellular_component	midbody
C	0031503	biological_process	protein-containing complex localization
C	0032991	cellular_component	protein-containing complex
C	0035281	biological_process	pre-miRNA export from nucleus
C	0036126	cellular_component	sperm flagellum
C	0042307	biological_process	positive regulation of protein import into nucleus
C	0042470	cellular_component	melanosome
C	0042565	cellular_component	RNA nuclear export complex
C	0044877	molecular_function	protein-containing complex binding
C	0045296	molecular_function	cadherin binding
C	0045505	molecular_function	dynein intermediate chain binding
C	0046039	biological_process	GTP metabolic process
C	0046872	molecular_function	metal ion binding
C	0046982	molecular_function	protein heterodimerization activity
C	0051301	biological_process	cell division
C	0055037	cellular_component	recycling endosome
C	0061015	biological_process	snRNA import into nucleus
C	0061676	molecular_function	importin-alpha family protein binding
C	0070062	cellular_component	extracellular exosome
C	0070883	molecular_function	pre-miRNA binding
C	0071389	biological_process	cellular response to mineralocorticoid stimulus
C	0090543	cellular_component	Flemming body
C	1902570	biological_process	protein localization to nucleolus
D	0000054	biological_process	ribosomal subunit export from nucleus
D	0000055	biological_process	ribosomal large subunit export from nucleus
D	0000056	biological_process	ribosomal small subunit export from nucleus
D	0000070	biological_process	mitotic sister chromatid segregation
D	0000166	molecular_function	nucleotide binding
D	0000278	biological_process	mitotic cell cycle
D	0000287	molecular_function	magnesium ion binding
D	0000785	cellular_component	chromatin
D	0001673	cellular_component	male germ cell nucleus
D	0002177	cellular_component	manchette
D	0003682	molecular_function	chromatin binding
D	0003723	molecular_function	RNA binding
D	0003924	molecular_function	GTPase activity
D	0003925	molecular_function	G protein activity
D	0005049	molecular_function	nuclear export signal receptor activity
D	0005515	molecular_function	protein binding
D	0005525	molecular_function	GTP binding
D	0005634	cellular_component	nucleus
D	0005635	cellular_component	nuclear envelope
D	0005643	cellular_component	nuclear pore
D	0005654	cellular_component	nucleoplasm
D	0005730	cellular_component	nucleolus
D	0005737	cellular_component	cytoplasm
D	0005814	cellular_component	centriole
D	0005829	cellular_component	cytosol
D	0006259	biological_process	DNA metabolic process
D	0006606	biological_process	protein import into nucleus
D	0006611	biological_process	protein export from nucleus
D	0006913	biological_process	nucleocytoplasmic transport
D	0007052	biological_process	mitotic spindle organization
D	0007286	biological_process	spermatid development
D	0008104	biological_process	intracellular protein localization
D	0015031	biological_process	protein transport
D	0016020	cellular_component	membrane
D	0016032	biological_process	viral process
D	0016787	molecular_function	hydrolase activity
D	0019003	molecular_function	GDP binding
D	0019904	molecular_function	protein domain specific binding
D	0021766	biological_process	hippocampus development
D	0030036	biological_process	actin cytoskeleton organization
D	0030496	cellular_component	midbody
D	0031503	biological_process	protein-containing complex localization
D	0032991	cellular_component	protein-containing complex
D	0035281	biological_process	pre-miRNA export from nucleus
D	0036126	cellular_component	sperm flagellum
D	0042307	biological_process	positive regulation of protein import into nucleus
D	0042470	cellular_component	melanosome
D	0042565	cellular_component	RNA nuclear export complex
D	0044877	molecular_function	protein-containing complex binding
D	0045296	molecular_function	cadherin binding
D	0045505	molecular_function	dynein intermediate chain binding
D	0046039	biological_process	GTP metabolic process
D	0046872	molecular_function	metal ion binding
D	0046982	molecular_function	protein heterodimerization activity
D	0051301	biological_process	cell division
D	0055037	cellular_component	recycling endosome
D	0061015	biological_process	snRNA import into nucleus
D	0061676	molecular_function	importin-alpha family protein binding
D	0070062	cellular_component	extracellular exosome
D	0070883	molecular_function	pre-miRNA binding
D	0071389	biological_process	cellular response to mineralocorticoid stimulus
D	0090543	cellular_component	Flemming body
D	1902570	biological_process	protein localization to nucleolus

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG D 1189

Chain	Residue
D	THR24
D	THR42
D	ASP65
D	GTP1190

---

site_id	AC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG C 1178

Chain	Residue
C	THR24
C	THR42
C	GTP1179

---

site_id	AC3
Number of Residues	22
Details	BINDING SITE FOR RESIDUE GTP D 1190

Chain	Residue
D	GLY22
D	LYS23
D	THR24
D	THR25
D	LYS37
D	LYS38
D	TYR39
D	ALA41
D	THR42
D	THR66
D	ALA67
D	GLY68
D	LEU69
D	ASN122
D	LYS123
D	ASP125
D	SER150
D	ALA151
D	LYS152
D	MG1189
D	GLY19
D	GLY20

---

site_id	AC4
Number of Residues	24
Details	BINDING SITE FOR RESIDUE GTP C 1179

Chain	Residue
C	GLY19
C	GLY20
C	THR21
C	GLY22
C	LYS23
C	THR24
C	THR25
C	LYS37
C	LYS38
C	TYR39
C	ALA41
C	THR42
C	THR66
C	ALA67
C	GLY68
C	LEU69
C	ASN122
C	LYS123
C	ASP125
C	ILE126
C	SER150
C	ALA151
C	LYS152
C	MG1178

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	16
Details	Region: {"description":"Switch-I","evidences":[{"source":"PROSITE-ProRule","id":"PRU00752","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	32
Details	Region: {"description":"Switch-II","evidences":[{"source":"PROSITE-ProRule","id":"PRU00752","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	14
Details	Binding site: {"evidences":[{"source":"PubMed","id":"10078529","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"10353245","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"10367892","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"11832950","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18611384","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19389996","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19505478","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24449914","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24915079","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26272610","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26349033","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28282025","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"7885480","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1IBR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1K5G","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1RRP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3CH5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GJ0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GJ3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GJ4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GJ5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GJ6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GJ7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GJ8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GJX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3NBY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3NBZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3NC0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3NC1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3ZJY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4C0Q","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OL0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5CIQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5CIT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5CIW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5CLQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DH9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DHA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DHF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DI9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DIF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DIS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DLQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWW","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"PubMed","id":"10078529","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"10353245","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"10367892","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"11832950","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19389996","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24449914","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24915079","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26272610","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26349033","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28282025","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"7885480","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1IBR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1K5D","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QBK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1RRP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GJX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3NBY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3NBZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3NC0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3NC1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3ZJY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4C0Q","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OL0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5CLL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5CLQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DH9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DHA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DHF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DI9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DIF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DIS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DLQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5JLJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWW","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"10078529","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"10353245","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"10367892","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"11832950","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18611384","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19389996","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19505478","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24449914","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24915079","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26272610","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26349033","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28282025","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"7885480","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1IBR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1K5D","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QBK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1RRP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GJX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3NBY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3NBZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3NC0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3NC1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3ZJY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4C0Q","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OL0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DH9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DHA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DHF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DI9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DIF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DIS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DLQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5JLJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWW","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	6
Details	Binding site: {"evidences":[{"source":"PubMed","id":"10078529","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"10353245","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"10367892","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"11832950","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18611384","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19389996","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19505478","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24449914","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24915079","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26272610","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26349033","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28282025","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"7885480","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1IBR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1K5D","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QBK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1RRP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3CH5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GJ0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GJ3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GJ4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GJ5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GJ6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GJ7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GJ8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GJX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3NBY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3NBZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3NC0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3NC1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3ZJY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4C0Q","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OL0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5CIQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5CIT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5CIW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5CJ2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5CLL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DH9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DHA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DHF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DI9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DIF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DIS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DLQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5JLJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWW","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"10078529","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"10353245","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"10367892","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"11832950","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18611384","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19389996","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19505478","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24449914","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24915079","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26272610","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26349033","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28282025","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"7885480","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1K5G","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3CH5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GJ0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GJ3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GJ4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GJ5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GJ6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GJ7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GJ8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GJX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3NBY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3NBZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3NC0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3NC1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3ZJY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4C0Q","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OL0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5CIQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5CIT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5CIW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5CJ2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5CLL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5CLQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DH9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DHA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DHF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DI9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DIF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DIS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5DLQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5JLJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5UWW","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	2
Details	Site: {"description":"Essential for GTP hydrolysis","evidences":[{"source":"PubMed","id":"18591255","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26272610","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"8636225","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	2
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	2
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"31075303","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	4
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI13
Number of Residues	2
Details	Modified residue: {"description":"N6-acetyllysine; alternate","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI14
Number of Residues	2
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"29040603","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI15
Number of Residues	2
Details	Modified residue: {"description":"N6-succinyllysine; alternate","evidences":[{"source":"UniProtKB","id":"P62827","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI16
Number of Residues	2
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate"}

Chain

Residue

Details

---

site_id	SWS_FT_FI17
Number of Residues	4
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---