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4BZY

Crystal structure of human glycogen branching enzyme (GBE1)

Functional Information from GO Data
ChainGOidnamespacecontents
A0003824molecular_functioncatalytic activity
A0003844molecular_function1,4-alpha-glucan branching enzyme activity
A0004553molecular_functionhydrolase activity, hydrolyzing O-glycosyl compounds
A0005515molecular_functionprotein binding
A0005737cellular_componentcytoplasm
A0005829cellular_componentcytosol
A0005975biological_processcarbohydrate metabolic process
A0005977biological_processglycogen metabolic process
A0005978biological_processglycogen biosynthetic process
A0006091biological_processgeneration of precursor metabolites and energy
A0016757molecular_functionglycosyltransferase activity
A0030246molecular_functioncarbohydrate binding
A0043169molecular_functioncation binding
A0043524biological_processnegative regulation of neuron apoptotic process
A0070062cellular_componentextracellular exosome
A0102752molecular_function1,4-alpha-glucan branching enzyme activity (using a glucosylated glycogenin as primer for glycogen synthesis)
B0003824molecular_functioncatalytic activity
B0003844molecular_function1,4-alpha-glucan branching enzyme activity
B0004553molecular_functionhydrolase activity, hydrolyzing O-glycosyl compounds
B0005515molecular_functionprotein binding
B0005737cellular_componentcytoplasm
B0005829cellular_componentcytosol
B0005975biological_processcarbohydrate metabolic process
B0005977biological_processglycogen metabolic process
B0005978biological_processglycogen biosynthetic process
B0006091biological_processgeneration of precursor metabolites and energy
B0016757molecular_functionglycosyltransferase activity
B0030246molecular_functioncarbohydrate binding
B0043169molecular_functioncation binding
B0043524biological_processnegative regulation of neuron apoptotic process
B0070062cellular_componentextracellular exosome
B0102752molecular_function1,4-alpha-glucan branching enzyme activity (using a glucosylated glycogenin as primer for glycogen synthesis)
C0003824molecular_functioncatalytic activity
C0003844molecular_function1,4-alpha-glucan branching enzyme activity
C0004553molecular_functionhydrolase activity, hydrolyzing O-glycosyl compounds
C0005515molecular_functionprotein binding
C0005737cellular_componentcytoplasm
C0005829cellular_componentcytosol
C0005975biological_processcarbohydrate metabolic process
C0005977biological_processglycogen metabolic process
C0005978biological_processglycogen biosynthetic process
C0006091biological_processgeneration of precursor metabolites and energy
C0016757molecular_functionglycosyltransferase activity
C0030246molecular_functioncarbohydrate binding
C0043169molecular_functioncation binding
C0043524biological_processnegative regulation of neuron apoptotic process
C0070062cellular_componentextracellular exosome
C0102752molecular_function1,4-alpha-glucan branching enzyme activity (using a glucosylated glycogenin as primer for glycogen synthesis)
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues3
DetailsACT_SITE: Nucleophile => ECO:0000250
ChainResidueDetails
AASP357
BASP357
CASP357

site_idSWS_FT_FI2
Number of Residues3
DetailsACT_SITE: Proton donor => ECO:0000250
ChainResidueDetails
AGLU412
BGLU412
CGLU412

site_idSWS_FT_FI3
Number of Residues12
DetailsBINDING: BINDING => ECO:0000305|PubMed:26199317, ECO:0007744|PDB:5CLT, ECO:0007744|PDB:5CLW
ChainResidueDetails
AASN62
CTRP91
CASP118
CGLU333
ATRP91
AASP118
AGLU333
BASN62
BTRP91
BASP118
BGLU333
CASN62

site_idSWS_FT_FI4
Number of Residues3
DetailsMOD_RES: N-acetylalanine => ECO:0007744|PubMed:22223895
ChainResidueDetails
AALA2
BALA2
CALA2

site_idSWS_FT_FI5
Number of Residues3
DetailsMOD_RES: Phosphotyrosine => ECO:0007744|PubMed:15592455
ChainResidueDetails
ATYR173
BTYR173
CTYR173

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PDB entries from 2024-05-01

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