4BY6

Yeast Not1-Not2-Not5 complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0017148	biological_process	negative regulation of translation
A	0030015	cellular_component	CCR4-NOT core complex
B	0000288	biological_process	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
B	0000289	biological_process	nuclear-transcribed mRNA poly(A) tail shortening
B	0000290	biological_process	deadenylation-dependent decapping of nuclear-transcribed mRNA
B	0000749	biological_process	response to pheromone triggering conjugation with cellular fusion
B	0003674	molecular_function	molecular_function
B	0005515	molecular_function	protein binding
B	0005634	cellular_component	nucleus
B	0005737	cellular_component	cytoplasm
B	0006351	biological_process	DNA-templated transcription
B	0006355	biological_process	regulation of DNA-templated transcription
B	0006368	biological_process	transcription elongation by RNA polymerase II
B	0016567	biological_process	protein ubiquitination
B	0030015	cellular_component	CCR4-NOT core complex
B	0031087	biological_process	deadenylation-independent decapping of nuclear-transcribed mRNA
B	0032968	biological_process	positive regulation of transcription elongation by RNA polymerase II
B	0051726	biological_process	regulation of cell cycle
C	0006355	biological_process	regulation of DNA-templated transcription
C	0030015	cellular_component	CCR4-NOT core complex
D	0017148	biological_process	negative regulation of translation
D	0030015	cellular_component	CCR4-NOT core complex
E	0000288	biological_process	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
E	0000289	biological_process	nuclear-transcribed mRNA poly(A) tail shortening
E	0000290	biological_process	deadenylation-dependent decapping of nuclear-transcribed mRNA
E	0000749	biological_process	response to pheromone triggering conjugation with cellular fusion
E	0003674	molecular_function	molecular_function
E	0005515	molecular_function	protein binding
E	0005634	cellular_component	nucleus
E	0005737	cellular_component	cytoplasm
E	0006351	biological_process	DNA-templated transcription
E	0006355	biological_process	regulation of DNA-templated transcription
E	0006368	biological_process	transcription elongation by RNA polymerase II
E	0016567	biological_process	protein ubiquitination
E	0030015	cellular_component	CCR4-NOT core complex
E	0031087	biological_process	deadenylation-independent decapping of nuclear-transcribed mRNA
E	0032968	biological_process	positive regulation of transcription elongation by RNA polymerase II
E	0051726	biological_process	regulation of cell cycle
F	0006355	biological_process	regulation of DNA-templated transcription
F	0030015	cellular_component	CCR4-NOT core complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL E 1192

Chain	Residue
E	GLU126
F	THR413
F	SER414
F	PHE417

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site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL B 1192

Chain	Residue
B	GLU126
C	THR413
C	SER414
C	PHE417

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site_id	AC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE PEG C 1561

Chain	Residue
C	LYS538
C	CYS511

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site_id	AC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE PEG F 1561

Chain	Residue
F	CYS511
F	LYS538

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site_id	AC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CA A 3080

Chain	Residue
A	ASP1915
A	ASP1918
A	ASP1931

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site_id	AC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CA D 3079

Chain	Residue
D	ASP1915
D	ASP1918
D	ASP1931

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site_id	AC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE ACT A 3081

Chain	Residue
A	ARG1707
A	ASN1710

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site_id	AC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE ACT D 3080

Chain	Residue
D	ARG1707
D	HIS1709
D	ASN1710

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"17330950","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"18407956","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"19779198","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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