4BVY
Crystal structure of the AIMP3-MRS N-terminal domain complex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004825 | molecular_function | methionine-tRNA ligase activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005634 | cellular_component | nucleus |
| B | 0005654 | cellular_component | nucleoplasm |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006412 | biological_process | translation |
| B | 0006418 | biological_process | tRNA aminoacylation for protein translation |
| B | 0008285 | biological_process | negative regulation of cell population proliferation |
| B | 0017101 | cellular_component | aminoacyl-tRNA synthetase multienzyme complex |
| B | 0043065 | biological_process | positive regulation of apoptotic process |
| B | 0043517 | biological_process | positive regulation of DNA damage response, signal transduction by p53 class mediator |
| B | 2000774 | biological_process | positive regulation of cellular senescence |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 124 |
| Details | Domain: {"description":"GST C-terminal"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 54 |
| Details | Region: {"description":"N-terminal"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | Region: {"description":"Linker"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 88 |
| Details | Region: {"description":"C-terminal"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"N-acetylalanine","evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"DEC-2008","submissionDatabase":"UniProtKB","authors":["Bienvenut W.V.","Calvo F.","Lilla S.","von Kriegsheim A.","Lempens A.","Kolch W."]}}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
