Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0017136 | molecular_function | NAD-dependent histone deacetylase activity |
| A | 0051287 | molecular_function | NAD binding |
| A | 0070403 | molecular_function | NAD+ binding |
| B | 0017136 | molecular_function | NAD-dependent histone deacetylase activity |
| B | 0051287 | molecular_function | NAD binding |
| B | 0070403 | molecular_function | NAD+ binding |
| C | 0017136 | molecular_function | NAD-dependent histone deacetylase activity |
| C | 0051287 | molecular_function | NAD binding |
| C | 0070403 | molecular_function | NAD+ binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE OCZ A 1393 |
| Chain | Residue |
| A | PRO155 |
| A | PHE293 |
| A | OAD1394 |
| A | HOH2018 |
| A | HOH2019 |
| A | PHE157 |
| A | PHE180 |
| A | GLN228 |
| A | ASN229 |
| A | ILE230 |
| A | ASP231 |
| A | HIS248 |
| A | ILE291 |
| site_id | AC2 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE OAD A 1394 |
| Chain | Residue |
| A | GLY145 |
| A | ALA146 |
| A | GLY147 |
| A | THR150 |
| A | ASP156 |
| A | PHE157 |
| A | ARG158 |
| A | TYR165 |
| A | PHE180 |
| A | GLN228 |
| A | HIS248 |
| A | PHE294 |
| A | GLY319 |
| A | THR320 |
| A | SER321 |
| A | VAL324 |
| A | ASN344 |
| A | ARG345 |
| A | GLY364 |
| A | ASP365 |
| A | VAL366 |
| A | OCZ1393 |
| A | HOH2018 |
| A | HOH2105 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 1395 |
| Chain | Residue |
| A | CYS256 |
| A | CYS259 |
| A | CYS280 |
| A | CYS283 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE NA A 1396 |
| Chain | Residue |
| A | ASP172 |
| A | HIS187 |
| C | HIS354 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL A 1397 |
| Chain | Residue |
| A | GLN138 |
| A | LEU222 |
| site_id | AC6 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE OCZ B 1392 |
| Chain | Residue |
| B | PHE157 |
| B | PHE180 |
| B | GLN228 |
| B | ASN229 |
| B | ILE230 |
| B | ASP231 |
| B | HIS248 |
| B | ILE291 |
| B | AR61393 |
| B | HOH2010 |
| B | HOH2011 |
| site_id | AC7 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE AR6 B 1393 |
| Chain | Residue |
| B | GLY145 |
| B | ALA146 |
| B | GLY147 |
| B | THR150 |
| B | ASP156 |
| B | PHE157 |
| B | ARG158 |
| B | TYR165 |
| B | GLN228 |
| B | HIS248 |
| B | PHE294 |
| B | GLY319 |
| B | THR320 |
| B | SER321 |
| B | VAL324 |
| B | ASN344 |
| B | ARG345 |
| B | GLY364 |
| B | ASP365 |
| B | VAL366 |
| B | OCZ1392 |
| B | HOH2010 |
| B | HOH2131 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 1394 |
| Chain | Residue |
| B | PRO310 |
| B | ALA312 |
| B | ARG335 |
| C | LYS190 |
| C | THR194 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 1395 |
| Chain | Residue |
| A | ASP127 |
| A | LEU131 |
| B | VAL236 |
| B | HOH2062 |
| B | HOH2082 |
| site_id | BC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN B 1396 |
| Chain | Residue |
| B | CYS256 |
| B | VAL258 |
| B | CYS259 |
| B | CYS280 |
| B | CYS283 |
| site_id | BC2 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE OCZ C 1394 |
| Chain | Residue |
| C | GLN228 |
| C | ASN229 |
| C | ILE230 |
| C | ASP231 |
| C | HIS248 |
| C | ILE291 |
| C | VAL292 |
| C | OAD1395 |
| C | HOH2018 |
| C | ILE154 |
| C | PRO155 |
| C | PHE157 |
| C | PHE180 |
| site_id | BC3 |
| Number of Residues | 26 |
| Details | BINDING SITE FOR RESIDUE OAD C 1395 |
| Chain | Residue |
| C | GLY145 |
| C | ALA146 |
| C | GLY147 |
| C | THR150 |
| C | ASP156 |
| C | PHE157 |
| C | ARG158 |
| C | SER159 |
| C | TYR165 |
| C | GLN228 |
| C | HIS248 |
| C | VAL292 |
| C | PHE294 |
| C | GLY319 |
| C | THR320 |
| C | SER321 |
| C | VAL324 |
| C | ASN344 |
| C | ARG345 |
| C | GLY364 |
| C | ASP365 |
| C | VAL366 |
| C | OCZ1394 |
| C | HOH2017 |
| C | HOH2143 |
| C | HOH2197 |
| site_id | BC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO C 1396 |
| Chain | Residue |
| C | LEU131 |
| C | ARG358 |
| C | THR391 |
| C | HOH2142 |
| site_id | BC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL C 1397 |
| Chain | Residue |
| C | ASP267 |
| C | GLU382 |
| C | ASP385 |
| C | HOH2193 |
| C | HOH2196 |
| site_id | BC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO C 1398 |
| Chain | Residue |
| B | THR150 |
| B | GLY153 |
| C | GLN300 |
| C | ARG301 |
| C | LEU304 |
| C | HOH2138 |
| site_id | BC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO C 1399 |
| Chain | Residue |
| C | LYS122 |
| C | ASP359 |
| site_id | BC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN C 1400 |
| Chain | Residue |
| C | CYS256 |
| C | CYS259 |
| C | CYS280 |
| C | CYS283 |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | HIS248 | |
| B | HIS248 | |
| C | HIS248 | |
| Chain | Residue | Details |
| A | ASN344 | |
| B | GLY145 | |
| B | GLN228 | |
| B | GLY319 | |
| B | ASN344 | |
| C | GLY145 | |
| C | GLN228 | |
| C | GLY319 | |
| C | ASN344 | |
| A | GLY145 | |
| A | GLN228 | |
| A | GLY319 | |
| Chain | Residue | Details |
| A | CYS256 | |
| A | CYS259 | |
| A | CYS280 | |
| A | CYS283 | |
| B | CYS256 | |
| B | CYS259 | |
| B | CYS280 | |
| B | CYS283 | |
| C | CYS256 | |
| C | CYS259 | |
| C | CYS280 | |
| C | CYS283 | |
| Chain | Residue | Details |
| A | LYS122 | |
| B | LYS122 | |
| C | LYS122 | |
