4BV8
Crystal structure of the apo form of mouse Mu-crystallin.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000122 | biological_process | negative regulation of transcription by RNA polymerase II |
| A | 0003714 | molecular_function | transcription corepressor activity |
| A | 0005634 | cellular_component | nucleus |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005739 | cellular_component | mitochondrion |
| A | 0005829 | cellular_component | cytosol |
| A | 0006839 | biological_process | mitochondrial transport |
| A | 0007605 | biological_process | sensory perception of sound |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0042403 | biological_process | thyroid hormone metabolic process |
| A | 0042562 | molecular_function | hormone binding |
| A | 0042803 | molecular_function | protein homodimerization activity |
| A | 0047125 | molecular_function | delta1-piperideine-2-carboxylate reductase activity |
| A | 0047127 | molecular_function | thiomorpholine-carboxylate dehydrogenase activity |
| A | 0050241 | molecular_function | pyrroline-2-carboxylate reductase activity |
| A | 0050661 | molecular_function | NADP binding |
| A | 0070324 | molecular_function | thyroid hormone binding |
| A | 0070327 | biological_process | thyroid hormone transport |
| B | 0000122 | biological_process | negative regulation of transcription by RNA polymerase II |
| B | 0003714 | molecular_function | transcription corepressor activity |
| B | 0005634 | cellular_component | nucleus |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005739 | cellular_component | mitochondrion |
| B | 0005829 | cellular_component | cytosol |
| B | 0006839 | biological_process | mitochondrial transport |
| B | 0007605 | biological_process | sensory perception of sound |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0042403 | biological_process | thyroid hormone metabolic process |
| B | 0042562 | molecular_function | hormone binding |
| B | 0042803 | molecular_function | protein homodimerization activity |
| B | 0047125 | molecular_function | delta1-piperideine-2-carboxylate reductase activity |
| B | 0047127 | molecular_function | thiomorpholine-carboxylate dehydrogenase activity |
| B | 0050241 | molecular_function | pyrroline-2-carboxylate reductase activity |
| B | 0050661 | molecular_function | NADP binding |
| B | 0070324 | molecular_function | thyroid hormone binding |
| B | 0070327 | biological_process | thyroid hormone transport |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL B 1312 |
| Chain | Residue |
| B | ASP70 |
| B | ALA71 |
| B | LEU106 |
| B | LYS303 |
| B | ASP307 |
| B | HOH2035 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE K B 1313 |
| Chain | Residue |
| B | CYS283 |
| B | LYS285 |
| B | THR287 |
| B | LEU130 |
| B | GLY219 |
| B | ALA220 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE K A 1313 |
| Chain | Residue |
| A | LEU130 |
| A | GLY219 |
| A | ALA220 |
| A | CYS283 |
| A | LYS285 |
| A | THR287 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"24467707","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4BVA","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"24467707","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4BV9","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 18 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"24467707","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4BV9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4BVA","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PDB","id":"4BV9","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PDB","id":"4BVA","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PDB","id":"4BV9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4BVA","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
