Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004843 | molecular_function | cysteine-type deubiquitinase activity |
A | 0016579 | biological_process | protein deubiquitination |
A | 0030433 | biological_process | ubiquitin-dependent ERAD pathway |
A | 0101005 | molecular_function | deubiquitinase activity |
D | 0004843 | molecular_function | cysteine-type deubiquitinase activity |
D | 0016579 | biological_process | protein deubiquitination |
D | 0030433 | biological_process | ubiquitin-dependent ERAD pathway |
D | 0101005 | molecular_function | deubiquitinase activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE GOL A 1309 |
Chain | Residue |
A | ALA187 |
A | GLN188 |
A | CYS210 |
A | LYS214 |
site_id | AC2 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE GOL D 1312 |
Chain | Residue |
D | ARG184 |
D | GLN188 |
D | LYS214 |
Functional Information from PROSITE/UniProt
site_id | PS00299 |
Number of Residues | 26 |
Details | UBIQUITIN_1 Ubiquitin domain signature. KakIqDkegIPpdqQrLIFaGkqleD |
Chain | Residue | Details |
B | LYS27-ASP52 | |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 6 |
Details | SITE: Interacts with activating enzyme |
Chain | Residue | Details |
B | ARG54 | |
B | ARG72 | |
C | ARG54 | |
C | ARG72 | |
E | ARG54 | |
E | ARG72 | |
site_id | SWS_FT_FI2 |
Number of Residues | 3 |
Details | SITE: Essential for function |
Chain | Residue | Details |
B | HIS68 | |
C | HIS68 | |
E | HIS68 | |
Chain | Residue | Details |
B | SER65 | |
C | SER65 | |
E | SER65 | |
Chain | Residue | Details |
B | THR66 | |
C | THR66 | |
E | THR66 | |
Chain | Residue | Details |
B | GLY76 | |
C | GLY76 | |
E | GLY76 | |
site_id | SWS_FT_FI6 |
Number of Residues | 3 |
Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:16443603 |
Chain | Residue | Details |
B | LYS6 | |
C | LYS6 | |
E | LYS6 | |
site_id | SWS_FT_FI7 |
Number of Residues | 6 |
Details | CROSSLNK: Glycyl lysine isopeptide (Gly-Lys) (interchain with K-? in acceptor proteins) |
Chain | Residue | Details |
B | GLY76 | |
C | GLY76 | |
E | GLY76 | |
Chain | Residue | Details |
B | LYS11 | |
B | LYS48 | |
C | LYS11 | |
C | LYS48 | |
E | LYS11 | |
E | LYS48 | |
site_id | SWS_FT_FI9 |
Number of Residues | 3 |
Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000305|PubMed:15466860 |
Chain | Residue | Details |
B | LYS27 | |
C | LYS27 | |
E | LYS27 | |
Chain | Residue | Details |
B | LYS29 | |
C | LYS29 | |
E | LYS29 | |
site_id | SWS_FT_FI11 |
Number of Residues | 3 |
Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:25752577 |
Chain | Residue | Details |
B | LYS33 | |
C | LYS33 | |
E | LYS33 | |
Chain | Residue | Details |
B | LYS63 | |
C | LYS63 | |
E | LYS63 | |