4BOY
Structure of GAPDH from Thermosynechococcus elongatus
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004365 | molecular_function | glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity |
| A | 0006006 | biological_process | glucose metabolic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0050661 | molecular_function | NADP binding |
| A | 0051287 | molecular_function | NAD binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004365 | molecular_function | glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity |
| B | 0006006 | biological_process | glucose metabolic process |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0050661 | molecular_function | NADP binding |
| B | 0051287 | molecular_function | NAD binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE NAD A 1001 |
| Chain | Residue |
| A | GLY8 |
| A | ALA99 |
| A | THR100 |
| A | GLY101 |
| A | PHE103 |
| A | THR123 |
| A | ALA124 |
| A | CYS154 |
| A | ASN317 |
| A | TYR321 |
| A | HOH2001 |
| A | PHE9 |
| A | HOH2002 |
| A | HOH2004 |
| A | HOH2037 |
| A | HOH2038 |
| A | HOH2076 |
| B | HOH2041 |
| A | GLY10 |
| A | ARG11 |
| A | ILE12 |
| A | ASN35 |
| A | ASP36 |
| A | THR37 |
| A | ARG81 |
| site_id | AC2 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE NAD B 1001 |
| Chain | Residue |
| A | HOH2045 |
| A | HOH2046 |
| B | GLY8 |
| B | PHE9 |
| B | GLY10 |
| B | ARG11 |
| B | ILE12 |
| B | ASN35 |
| B | ASP36 |
| B | THR37 |
| B | ARG81 |
| B | ALA99 |
| B | THR100 |
| B | GLY101 |
| B | THR123 |
| B | ALA124 |
| B | ASN317 |
| B | TYR321 |
| B | HOH2003 |
| B | HOH2004 |
| B | HOH2017 |
| B | HOH2034 |
| B | HOH2070 |
| B | HOH2072 |
| B | HOH2073 |
Functional Information from PROSITE/UniProt
| site_id | PS00071 |
| Number of Residues | 8 |
| Details | GAPDH Glyceraldehyde 3-phosphate dehydrogenase active site. ASCTTNcL |
| Chain | Residue | Details |
| A | ALA152-LEU159 |
