4BM1
CRYSTAL STRUCTURE OF MANGANESE PEROXIDASE 4 FROM PLEUROTUS OSTREATUS - CRYSTAL FORM I
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000302 | biological_process | response to reactive oxygen species |
| A | 0004601 | molecular_function | peroxidase activity |
| A | 0005576 | cellular_component | extracellular region |
| A | 0006979 | biological_process | response to oxidative stress |
| A | 0020037 | molecular_function | heme binding |
| A | 0034599 | biological_process | cellular response to oxidative stress |
| A | 0042744 | biological_process | hydrogen peroxide catabolic process |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0098869 | biological_process | cellular oxidant detoxification |
| B | 0000302 | biological_process | response to reactive oxygen species |
| B | 0004601 | molecular_function | peroxidase activity |
| B | 0005576 | cellular_component | extracellular region |
| B | 0006979 | biological_process | response to oxidative stress |
| B | 0020037 | molecular_function | heme binding |
| B | 0034599 | biological_process | cellular response to oxidative stress |
| B | 0042744 | biological_process | hydrogen peroxide catabolic process |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0098869 | biological_process | cellular oxidant detoxification |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 401 |
| Chain | Residue |
| A | ASP49 |
| A | GLY67 |
| A | ASP69 |
| A | SER71 |
| A | HOH2119 |
| A | HOH2133 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA A 402 |
| Chain | Residue |
| A | ASP199 |
| A | ASP201 |
| A | SER177 |
| A | ASP194 |
| A | THR196 |
| site_id | AC3 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE HEM A 500 |
| Chain | Residue |
| A | HIS40 |
| A | GLU41 |
| A | ARG44 |
| A | PHE47 |
| A | GLU147 |
| A | PRO148 |
| A | LEU172 |
| A | LEU173 |
| A | SER175 |
| A | HIS176 |
| A | ALA179 |
| A | ALA180 |
| A | GLN181 |
| A | ASP182 |
| A | THR183 |
| A | ILE184 |
| A | PHE193 |
| A | LEU235 |
| A | SER237 |
| A | MET269 |
| A | HOH2093 |
| A | HOH2094 |
| A | HOH2377 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA B 401 |
| Chain | Residue |
| B | ASP49 |
| B | GLY67 |
| B | ASP69 |
| B | SER71 |
| B | HOH2108 |
| B | HOH2120 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA B 402 |
| Chain | Residue |
| B | SER177 |
| B | ASP194 |
| B | THR196 |
| B | ASP199 |
| B | ASP201 |
| site_id | AC6 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE HEM B 500 |
| Chain | Residue |
| B | HIS40 |
| B | GLU41 |
| B | ARG44 |
| B | PHE47 |
| B | GLU147 |
| B | PRO148 |
| B | LEU172 |
| B | LEU173 |
| B | SER175 |
| B | HIS176 |
| B | ALA179 |
| B | ALA180 |
| B | GLN181 |
| B | ASP182 |
| B | THR183 |
| B | ILE184 |
| B | PHE193 |
| B | LEU235 |
| B | SER237 |
| B | MET269 |
| B | HOH2083 |
| B | HOH2097 |
| B | HOH2142 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1339 |
| Chain | Residue |
| A | SER5 |
| A | LYS6 |
| A | HOH2003 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1340 |
| Chain | Residue |
| A | GLU34 |
| A | CYS35 |
| A | HOH2081 |
| A | HOH2293 |
| A | HOH2401 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1341 |
| Chain | Residue |
| A | LYS62 |
| A | PHE63 |
| A | HOH2167 |
| A | HOH2608 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1342 |
| Chain | Residue |
| A | GLY294 |
| A | ARG295 |
| A | HOH2524 |
| A | HOH2609 |
| site_id | BC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1343 |
| Chain | Residue |
| A | ARG295 |
| A | LYS297 |
| A | GLN298 |
| A | HOH2529 |
| A | HOH2532 |
| site_id | BC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1344 |
| Chain | Residue |
| A | ALA303 |
| A | THR328 |
| A | PHE329 |
| A | HOH2536 |
| A | HOH2539 |
| A | HOH2588 |
| site_id | BC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1345 |
| Chain | Residue |
| B | LYS101 |
| A | LYS316 |
| A | GLY327 |
| A | THR328 |
| A | HOH2610 |
| site_id | BC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1339 |
| Chain | Residue |
| A | LYS281 |
| A | HOH2068 |
| B | ARG321 |
| B | PRO323 |
| B | HOH2537 |
| site_id | BC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1346 |
| Chain | Residue |
| A | ARG321 |
| A | PRO323 |
| A | HOH2576 |
| A | HOH2579 |
| B | LYS281 |
| B | HOH2058 |
| site_id | BC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1340 |
| Chain | Residue |
| A | HOH2251 |
| B | THR328 |
| B | PHE329 |
| B | THR330 |
| B | HOH2330 |
| B | HOH2500 |
| B | HOH2550 |
| site_id | BC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1341 |
| Chain | Residue |
| B | ASP325 |
| B | LYS326 |
| B | HOH2540 |
| site_id | BC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1342 |
| Chain | Residue |
| B | ALA303 |
| B | THR328 |
| B | PHE329 |
| B | HOH2501 |
| B | HOH2506 |
| B | HOH2547 |
| site_id | CC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1347 |
| Chain | Residue |
| A | ASN12 |
| A | ILE283 |
| A | ASP284 |
| A | HOH2029 |
| A | HOH2031 |
| A | HOH2509 |
| site_id | CC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1343 |
| Chain | Residue |
| B | ASN12 |
| B | ILE283 |
| B | ASP284 |
| B | HOH2024 |
| B | HOH2476 |
| B | HOH2571 |
| site_id | CC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1344 |
| Chain | Residue |
| B | ARG126 |
| B | GLU287 |
| B | HOH2480 |
| B | HOH2482 |
| site_id | CC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1345 |
| Chain | Residue |
| A | LYS101 |
| B | LYS316 |
| B | GLY327 |
| B | THR328 |
| B | HOH2429 |
| B | HOH2572 |
| B | HOH2573 |
| B | HOH2574 |
| site_id | CC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1348 |
| Chain | Residue |
| A | ASP325 |
| A | LYS326 |
| A | HOH2580 |
| A | HOH2614 |
| site_id | CC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1346 |
| Chain | Residue |
| B | LYS62 |
| B | PHE63 |
| B | HOH2153 |
| B | HOH2576 |
| site_id | CC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1347 |
| Chain | Residue |
| B | ARG126 |
| B | HOH2450 |
| B | HOH2577 |
| B | HOH2578 |
| site_id | CC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1348 |
| Chain | Residue |
| B | GLY294 |
| B | ARG295 |
| B | HOH2490 |
| B | HOH2579 |
| site_id | CC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1349 |
| Chain | Residue |
| B | ARG295 |
| B | LYS297 |
| B | GLN298 |
| B | HOH2492 |
| B | HOH2497 |
| site_id | DC1 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE CIT B 1350 |
| Chain | Residue |
| B | ILE215 |
| B | PRO216 |
| B | PRO230 |
| B | GLY231 |
| B | HOH2354 |
| B | HOH2386 |
| B | HOH2402 |
| B | HOH2404 |
| B | HOH2580 |
| B | HOH2581 |
| B | HOH2582 |
| site_id | DC2 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE CIT A 1349 |
| Chain | Residue |
| A | ILE215 |
| A | PRO216 |
| A | PRO230 |
| A | GLY231 |
| A | HOH2389 |
| A | HOH2422 |
| A | HOH2439 |
| A | HOH2441 |
| A | HOH2615 |
| A | HOH2616 |
| A | HOH2617 |
| A | HOH2618 |
Functional Information from PROSITE/UniProt
