Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0003723 | molecular_function | RNA binding |
| A | 0005515 | molecular_function | protein binding |
| A | 0005829 | cellular_component | cytosol |
| A | 0006364 | biological_process | rRNA processing |
| A | 0008168 | molecular_function | methyltransferase activity |
| A | 0008649 | molecular_function | rRNA methyltransferase activity |
| A | 0008988 | molecular_function | rRNA (adenine-N6-)-methyltransferase activity |
| A | 0015976 | biological_process | carbon utilization |
| A | 0016740 | molecular_function | transferase activity |
| A | 0032259 | biological_process | methylation |
| A | 0036307 | molecular_function | 23S rRNA (adenine(2030)-N(6))-methyltransferase activity |
| A | 0070475 | biological_process | rRNA base methylation |
| B | 0003676 | molecular_function | nucleic acid binding |
| B | 0003723 | molecular_function | RNA binding |
| B | 0005515 | molecular_function | protein binding |
| B | 0005829 | cellular_component | cytosol |
| B | 0006364 | biological_process | rRNA processing |
| B | 0008168 | molecular_function | methyltransferase activity |
| B | 0008649 | molecular_function | rRNA methyltransferase activity |
| B | 0008988 | molecular_function | rRNA (adenine-N6-)-methyltransferase activity |
| B | 0015976 | biological_process | carbon utilization |
| B | 0016740 | molecular_function | transferase activity |
| B | 0032259 | biological_process | methylation |
| B | 0036307 | molecular_function | 23S rRNA (adenine(2030)-N(6))-methyltransferase activity |
| B | 0070475 | biological_process | rRNA base methylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE SAM A 1281 |
| Chain | Residue |
| A | LEU2 |
| A | GLY99 |
| A | SER100 |
| A | GLU118 |
| A | LEU119 |
| A | HIS120 |
| A | ALA142 |
| A | ASP143 |
| A | GLY144 |
| A | ASP164 |
| A | HOH2002 |
| A | TYR4 |
| A | HOH2007 |
| A | HOH2058 |
| A | HOH2059 |
| A | HIS6 |
| A | LYS18 |
| A | HIS19 |
| A | THR41 |
| A | HIS42 |
| A | ALA43 |
| A | GLY44 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GOL A 1282 |
| Chain | Residue |
| A | LYS30 |
| A | LEU106 |
| A | LEU107 |
| A | LEU108 |
| A | ARG109 |
| A | HOH2120 |
| A | HOH2239 |
| A | HOH2240 |
| B | ARG90 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PEG A 1283 |
| Chain | Residue |
| A | VAL199 |
| A | LEU200 |
| A | ARG201 |
| A | ASP229 |
| A | SER230 |
| A | HOH2192 |
| A | HOH2195 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 1284 |
| Chain | Residue |
| A | HIS13 |
| A | MET235 |
| A | EDO1285 |
| A | HOH2066 |
| A | HOH2067 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 1285 |
| Chain | Residue |
| A | HIS13 |
| A | GLU63 |
| A | EDO1284 |
| A | HOH2020 |
| A | HOH2071 |
| A | HOH2072 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 1286 |
| Chain | Residue |
| A | VAL226 |
| A | LEU227 |
| A | VAL265 |
| A | ALA267 |
| A | THR269 |
| A | HOH2231 |
| site_id | AC7 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO A 1287 |
| Chain | Residue |
| A | HIS6 |
| A | HIS9 |
| A | ASN12 |
| A | ALA14 |
| A | ASP15 |
| A | MET235 |
| A | HOH2004 |
| A | HOH2023 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 1288 |
| Chain | Residue |
| A | ARG201 |
| A | GLU223 |
| A | HIS271 |
| A | THR273 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 1289 |
| Chain | Residue |
| A | PRO228 |
| A | ASP229 |
| A | GLY270 |
| A | HIS271 |
| site_id | BC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 1290 |
| Chain | Residue |
| A | ARG128 |
| A | PHE131 |
| A | GLN132 |
| A | VAL139 |
| A | HOH2139 |
| A | HOH2141 |
| site_id | BC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 1291 |
| Chain | Residue |
| A | THR189 |
| A | ILE191 |
| A | ASN244 |
| A | PRO245 |
| A | SO41297 |
| A | HOH2241 |
| site_id | BC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 1292 |
| Chain | Residue |
| A | PHE145 |
| A | ALA175 |
| A | HOH2150 |
| A | HOH2178 |
| site_id | BC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 1293 |
| Chain | Residue |
| A | SER3 |
| A | TYR4 |
| A | GLU168 |
| A | HOH2167 |
| site_id | BC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 1294 |
| Chain | Residue |
| A | SER7 |
| A | ALA45 |
| A | ARG47 |
| A | TYR48 |
| A | GLN49 |
| A | LEU126 |
| A | HOH2135 |
| site_id | BC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 1295 |
| Chain | Residue |
| A | TRP247 |
| A | LEU249 |
| A | GLU250 |
| A | TRP276 |
| A | HOH2218 |
| A | HOH2219 |
| A | PRO246 |
| site_id | BC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 1296 |
| Chain | Residue |
| A | ARG95 |
| A | LYS149 |
| A | ALA150 |
| A | LYS151 |
| A | LEU152 |
| A | PRO153 |
| A | HOH2113 |
| site_id | BC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1297 |
| Chain | Residue |
| A | LEU29 |
| A | LYS32 |
| A | ARG158 |
| A | EDO1291 |
| A | HOH2037 |
| A | HOH2162 |
| A | HOH2241 |
| site_id | BC9 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1298 |
| Chain | Residue |
| A | ARG47 |
| A | HIS87 |
| A | PHE88 |
| A | HOH2101 |
| A | HOH2117 |
| A | HOH2243 |
| B | HIS87 |
| B | ARG105 |
| site_id | CC1 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE SAM B 1281 |
| Chain | Residue |
| B | LYS18 |
| B | HIS19 |
| B | THR41 |
| B | HIS42 |
| B | ALA43 |
| B | GLY44 |
| B | GLY99 |
| B | SER100 |
| B | GLU118 |
| B | LEU119 |
| B | HIS120 |
| B | ALA142 |
| B | ASP143 |
| B | GLY144 |
| B | ASP164 |
| B | HOH2016 |
| B | HOH2038 |
| B | HOH2039 |
| B | HOH2094 |
| site_id | CC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PEG B 1282 |
| Chain | Residue |
| B | MET169 |
| B | THR171 |
| B | ASP172 |
| B | EDO1286 |
| site_id | CC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO B 1283 |
| Chain | Residue |
| B | ARG201 |
| B | ILE208 |
| B | GLN221 |
| B | EDO1296 |
| B | HOH2139 |
| B | HOH2188 |
| B | HOH2189 |
| site_id | CC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO B 1284 |
| Chain | Residue |
| B | PRO228 |
| B | ASP229 |
| B | GLY270 |
| B | HIS271 |
| B | HOH2140 |
| B | HOH2190 |
| site_id | CC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 1285 |
| Chain | Residue |
| B | ALA66 |
| B | TRP69 |
| B | EDO1289 |
| B | HOH2132 |
| B | HOH2191 |
| site_id | CC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO B 1286 |
| Chain | Residue |
| B | PHE145 |
| B | PRO165 |
| B | PRO166 |
| B | ASP172 |
| B | PEG1282 |
| B | HOH2037 |
| site_id | CC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 1287 |
| Chain | Residue |
| B | THR214 |
| B | GLY215 |
| B | ILE216 |
| B | HOH2060 |
| B | HOH2147 |
| site_id | CC8 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE EDO B 1288 |
| site_id | CC9 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE EDO B 1289 |
| Chain | Residue |
| B | TYR61 |
| B | LEU62 |
| B | ALA66 |
| B | LEU94 |
| B | PRO153 |
| B | ARG186 |
| B | EDO1285 |
| B | HOH2049 |
| B | HOH2051 |
| site_id | DC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 1290 |
| Chain | Residue |
| B | TRP247 |
| B | GLU250 |
| B | TRP276 |
| B | HOH2164 |
| site_id | DC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 1291 |
| Chain | Residue |
| B | ALA76 |
| B | GLU77 |
| B | GLU79 |
| B | ALA80 |
| B | HOH2020 |
| site_id | DC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO B 1292 |
| Chain | Residue |
| B | HIS261 |
| B | SER262 |
| B | VAL265 |
| B | GLY268 |
| B | HOH2179 |
| B | HOH2193 |
| site_id | DC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO B 1293 |
| Chain | Residue |
| B | PHE145 |
| B | LYS149 |
| B | SER178 |
| B | GLY179 |
| B | GLU182 |
| B | HOH2122 |
| B | HOH2194 |
| site_id | DC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO B 1294 |
| Chain | Residue |
| B | ALA181 |
| B | THR214 |
| B | HOH2124 |
| site_id | DC6 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE EDO B 1295 |
| site_id | DC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO B 1296 |
| Chain | Residue |
| A | HOH2170 |
| B | ILE208 |
| B | GLU212 |
| B | GLN221 |
| B | EDO1283 |
| B | HOH2188 |
| B | HOH2189 |
Functional Information from PROSITE/UniProt
| site_id | PS00092 |
| Number of Residues | 7 |
| Details | N6_MTASE N-6 Adenine-specific DNA methylases signature. ILIDPPY |
| Chain | Residue | Details |
| A | ILE161-TYR167 | |
| A | ILE241-TRP247 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PubMed","id":"23945937","evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"23945937","evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Site: {"description":"Interaction with substrate rRNA","evidences":[{"evidenceCode":"ECO:0000305"}]} |
