4BL0
Crystal structure of yeast Bub3-Bub1 bound to phospho-Spc105
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000775 | cellular_component | chromosome, centromeric region |
| A | 0000776 | cellular_component | kinetochore |
| A | 0005515 | molecular_function | protein binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005654 | cellular_component | nucleoplasm |
| A | 0005694 | cellular_component | chromosome |
| A | 0007094 | biological_process | mitotic spindle assembly checkpoint signaling |
| A | 0033597 | cellular_component | mitotic checkpoint complex |
| A | 0043130 | molecular_function | ubiquitin binding |
| A | 0044774 | biological_process | mitotic DNA integrity checkpoint signaling |
| A | 1902499 | biological_process | positive regulation of protein autoubiquitination |
| A | 1990298 | cellular_component | bub1-bub3 complex |
| D | 0000775 | cellular_component | chromosome, centromeric region |
| D | 0000776 | cellular_component | kinetochore |
| D | 0005515 | molecular_function | protein binding |
| D | 0005634 | cellular_component | nucleus |
| D | 0005654 | cellular_component | nucleoplasm |
| D | 0005694 | cellular_component | chromosome |
| D | 0007094 | biological_process | mitotic spindle assembly checkpoint signaling |
| D | 0033597 | cellular_component | mitotic checkpoint complex |
| D | 0043130 | molecular_function | ubiquitin binding |
| D | 0044774 | biological_process | mitotic DNA integrity checkpoint signaling |
| D | 1902499 | biological_process | positive regulation of protein autoubiquitination |
| D | 1990298 | cellular_component | bub1-bub3 complex |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG A 1341 |
| Chain | Residue |
| A | ASP198 |
| A | VAL199 |
| A | ILE257 |
| A | GLU258 |
| A | HOH2071 |
| A | HOH2084 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG D 1341 |
| Chain | Residue |
| D | GLU258 |
| D | HOH2067 |
| D | HOH2082 |
| D | ASP198 |
| D | VAL199 |
| D | ILE257 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 78 |
| Details | Repeat: {"description":"WD 1"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 84 |
| Details | Repeat: {"description":"WD 2"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 80 |
| Details | Repeat: {"description":"WD 3"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 82 |
| Details | Repeat: {"description":"WD 4"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 78 |
| Details | Repeat: {"description":"WD 6"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 74 |
| Details | Repeat: {"description":"WD 7"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 6 |
| Details | Motif: {"description":"MELT; degenerate","evidences":[{"source":"PubMed","id":"22521787","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"24066227","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphothreonine; by MPS1","evidences":[{"source":"PubMed","id":"22521787","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
