4BKA

crystal structure of the human EphA4 ectodomain in complex with human ephrin A5

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005003	molecular_function	ephrin receptor activity
A	0005524	molecular_function	ATP binding
A	0006468	biological_process	protein phosphorylation
A	0007169	biological_process	cell surface receptor protein tyrosine kinase signaling pathway
A	0016020	cellular_component	membrane
C	0016020	cellular_component	membrane
C	0046875	molecular_function	ephrin receptor binding
C	0048013	biological_process	ephrin receptor signaling pathway

Functional Information from PROSITE/UniProt

site_id	PS00790
Number of Residues	21
Details	RECEPTOR_TYR_KIN_V_1 Receptor tyrosine kinase class V signature 1. FqDvGACIALVSVRVfykKCP

Chain	Residue	Details
A	PHE185-PRO205

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site_id	PS00791
Number of Residues	21
Details	RECEPTOR_TYR_KIN_V_2 Receptor tyrosine kinase class V signature 2. CgaDGEWlv.PIGnClCnaGHE

Chain	Residue	Details
A	CYS247-GLU267

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site_id	PS01299
Number of Residues	28
Details	EPHRIN_RBD_1 Ephrin receptor-binding (ephrin RBD) domain signature. KFSeKFQlFTPfslGfEFrpgreYFyiS

Chain	Residue	Details
C	LYS117-SER144

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:17400922

Chain	Residue	Details
C	ASN41

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site_id	SWS_FT_FI2
Number of Residues	4
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255

Chain	Residue	Details
A	ASN235
A	ASN340
A	ASN408
A	ASN545

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