Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

4BFQ

Assembly of a triple pi-stack of ligands in the binding site of Aplysia californica acetylcholine binding protein (AChBP)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004888	molecular_function	transmembrane signaling receptor activity
A	0005216	molecular_function	monoatomic ion channel activity
A	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
A	0005231	molecular_function	excitatory extracellular ligand-gated monoatomic ion channel activity
A	0005515	molecular_function	protein binding
A	0006811	biological_process	monoatomic ion transport
A	0007165	biological_process	signal transduction
A	0007268	biological_process	chemical synaptic transmission
A	0016020	cellular_component	membrane
A	0034220	biological_process	monoatomic ion transmembrane transport
A	0042391	biological_process	regulation of membrane potential
A	0042802	molecular_function	identical protein binding
A	0043005	cellular_component	neuron projection
A	0045202	cellular_component	synapse
A	0046872	molecular_function	metal ion binding
A	0050877	biological_process	nervous system process
A	0060078	biological_process	regulation of postsynaptic membrane potential
A	0060079	biological_process	excitatory postsynaptic potential
A	0098794	cellular_component	postsynapse
A	1904315	molecular_function	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
B	0004888	molecular_function	transmembrane signaling receptor activity
B	0005216	molecular_function	monoatomic ion channel activity
B	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
B	0005231	molecular_function	excitatory extracellular ligand-gated monoatomic ion channel activity
B	0005515	molecular_function	protein binding
B	0006811	biological_process	monoatomic ion transport
B	0007165	biological_process	signal transduction
B	0007268	biological_process	chemical synaptic transmission
B	0016020	cellular_component	membrane
B	0034220	biological_process	monoatomic ion transmembrane transport
B	0042391	biological_process	regulation of membrane potential
B	0042802	molecular_function	identical protein binding
B	0043005	cellular_component	neuron projection
B	0045202	cellular_component	synapse
B	0046872	molecular_function	metal ion binding
B	0050877	biological_process	nervous system process
B	0060078	biological_process	regulation of postsynaptic membrane potential
B	0060079	biological_process	excitatory postsynaptic potential
B	0098794	cellular_component	postsynapse
B	1904315	molecular_function	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
C	0004888	molecular_function	transmembrane signaling receptor activity
C	0005216	molecular_function	monoatomic ion channel activity
C	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
C	0005231	molecular_function	excitatory extracellular ligand-gated monoatomic ion channel activity
C	0005515	molecular_function	protein binding
C	0006811	biological_process	monoatomic ion transport
C	0007165	biological_process	signal transduction
C	0007268	biological_process	chemical synaptic transmission
C	0016020	cellular_component	membrane
C	0034220	biological_process	monoatomic ion transmembrane transport
C	0042391	biological_process	regulation of membrane potential
C	0042802	molecular_function	identical protein binding
C	0043005	cellular_component	neuron projection
C	0045202	cellular_component	synapse
C	0046872	molecular_function	metal ion binding
C	0050877	biological_process	nervous system process
C	0060078	biological_process	regulation of postsynaptic membrane potential
C	0060079	biological_process	excitatory postsynaptic potential
C	0098794	cellular_component	postsynapse
C	1904315	molecular_function	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
D	0004888	molecular_function	transmembrane signaling receptor activity
D	0005216	molecular_function	monoatomic ion channel activity
D	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
D	0005231	molecular_function	excitatory extracellular ligand-gated monoatomic ion channel activity
D	0005515	molecular_function	protein binding
D	0006811	biological_process	monoatomic ion transport
D	0007165	biological_process	signal transduction
D	0007268	biological_process	chemical synaptic transmission
D	0016020	cellular_component	membrane
D	0034220	biological_process	monoatomic ion transmembrane transport
D	0042391	biological_process	regulation of membrane potential
D	0042802	molecular_function	identical protein binding
D	0043005	cellular_component	neuron projection
D	0045202	cellular_component	synapse
D	0046872	molecular_function	metal ion binding
D	0050877	biological_process	nervous system process
D	0060078	biological_process	regulation of postsynaptic membrane potential
D	0060079	biological_process	excitatory postsynaptic potential
D	0098794	cellular_component	postsynapse
D	1904315	molecular_function	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
E	0004888	molecular_function	transmembrane signaling receptor activity
E	0005216	molecular_function	monoatomic ion channel activity
E	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
E	0005231	molecular_function	excitatory extracellular ligand-gated monoatomic ion channel activity
E	0005515	molecular_function	protein binding
E	0006811	biological_process	monoatomic ion transport
E	0007165	biological_process	signal transduction
E	0007268	biological_process	chemical synaptic transmission
E	0016020	cellular_component	membrane
E	0034220	biological_process	monoatomic ion transmembrane transport
E	0042391	biological_process	regulation of membrane potential
E	0042802	molecular_function	identical protein binding
E	0043005	cellular_component	neuron projection
E	0045202	cellular_component	synapse
E	0046872	molecular_function	metal ion binding
E	0050877	biological_process	nervous system process
E	0060078	biological_process	regulation of postsynaptic membrane potential
E	0060079	biological_process	excitatory postsynaptic potential
E	0098794	cellular_component	postsynapse
E	1904315	molecular_function	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE 083 A 301

Chain	Residue
A	TYR91
A	TYR186
A	CYS188
A	CYS189
A	TYR193
A	083302
A	HOH2009
B	SER164

site_id	AC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE 083 A 302

Chain	Residue
A	TYR193
A	083301
A	083303
A	HOH2019
B	TYR53
B	SER164
A	TYR91

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE 083 A 303

Chain	Residue
A	VAL146
A	083302
B	TYR53
B	GLN55
B	MET114
B	ASP162

site_id	AC4
Number of Residues	9
Details	BINDING SITE FOR RESIDUE 083 B 301

Chain	Residue
B	TYR91
B	SER144
B	TYR186
B	CYS188
B	TYR193
B	083302
C	TYR53
C	ASP162
C	SER164

site_id	AC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE 083 B 302

Chain	Residue
B	TRP145
B	083301
C	GLN55

site_id	AC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE 083 C 301

Chain	Residue
C	GLN184
C	TYR186
C	CYS188
C	TYR193
C	083302
D	SER164

site_id	AC7
Number of Residues	8
Details	BINDING SITE FOR RESIDUE 083 C 302

Chain	Residue
C	TYR91
C	SER144
C	TYR193
C	083301
C	083303
D	TYR53
D	ASP162
D	SER164

site_id	AC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE 083 C 303

Chain	Residue
C	VAL146
C	083302
D	GLN55
D	ARG77
D	VAL106
D	MET114

site_id	AC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE 083 D 301

Chain	Residue
D	TYR91
D	TYR186
D	TYR193
D	083302
E	SER164

site_id	BC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE 083 D 302

Chain	Residue
D	TYR91
D	SER144
D	TRP145
D	083301
D	083303
E	TYR53
E	SER164

site_id	BC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE 083 D 303

Chain	Residue
D	VAL146
D	083302
E	GLN55
E	VAL106
E	MET114

site_id	BC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE 083 E 301

Chain	Residue
E	TYR91
E	TYR186
E	CYS188
E	TYR193
E	083302

site_id	BC4
Number of Residues	7
Details	BINDING SITE FOR RESIDUE 083 E 302

Chain	Residue
A	TYR53
A	SER164
E	TYR91
E	SER144
E	TRP145
E	083301
E	083303

site_id	BC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE 083 E 303

Chain	Residue
A	TYR53
A	GLN55
A	VAL106
A	MET114
E	VAL146
E	083302

site_id	BC6
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL D 1206

Chain	Residue
D	PRO19
D	TRP84
D	TYR147
D	HOH2012
E	LYS8
E	ARG77
E	SER79

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)