4BD4

Monomeric Human Cu,Zn Superoxide dismutase, loops IV and VII deleted, apo form, mutant H43F

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005507	molecular_function	copper ion binding
A	0006801	biological_process	superoxide metabolic process
A	0046872	molecular_function	metal ion binding
B	0005507	molecular_function	copper ion binding
B	0006801	biological_process	superoxide metabolic process
B	0046872	molecular_function	metal ion binding
C	0005507	molecular_function	copper ion binding
C	0006801	biological_process	superoxide metabolic process
C	0046872	molecular_function	metal ion binding
D	0005507	molecular_function	copper ion binding
D	0006801	biological_process	superoxide metabolic process
D	0046872	molecular_function	metal ion binding
E	0005507	molecular_function	copper ion binding
E	0006801	biological_process	superoxide metabolic process
E	0046872	molecular_function	metal ion binding
F	0005507	molecular_function	copper ion binding
F	0006801	biological_process	superoxide metabolic process
F	0046872	molecular_function	metal ion binding
G	0005507	molecular_function	copper ion binding
G	0006801	biological_process	superoxide metabolic process
G	0046872	molecular_function	metal ion binding
H	0005507	molecular_function	copper ion binding
H	0006801	biological_process	superoxide metabolic process
H	0046872	molecular_function	metal ion binding
I	0005507	molecular_function	copper ion binding
I	0006801	biological_process	superoxide metabolic process
I	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE GOL B 1110

Chain	Residue
B	ASP71
B	ILE74
F	ALA50

---

site_id	AC2
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GOL A 1110

Chain	Residue
E	ALA50
E	ASP71
A	ALA50
A	GLY52
A	LEU54
A	ASP71
A	HOH2005
A	HOH2015

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL G 1109

Chain	Residue
C	ASP53
G	LEU54
G	ASP71
G	HOH2001

---

site_id	AC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE GOL H 1111

Chain	Residue
H	GLY52
H	LEU54
H	ASP71

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	27
Details	Binding site: {"evidences":[{"source":"PubMed","id":"12963370","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17548825","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	9
Details	Binding site: {"evidences":[{"source":"PubMed","id":"20727846","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	7
Details	Modified residue: {"description":"N-acetylalanine","evidences":[{"source":"PubMed","id":"1463506","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"7002610","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25944712","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	27
Details	Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"UniProtKB","id":"P08228","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	9
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	9
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	9
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P07632","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	9
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P08228","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	7
Details	Modified residue: {"description":"N6-succinyllysine; alternate","evidences":[{"source":"PubMed","id":"24140062","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	9
Details	Lipidation: {"description":"S-palmitoyl cysteine","evidences":[{"source":"PubMed","id":"22496122","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	18
Details	Cross-link: {"description":"1-(tryptophan-3-yl)-tryptophan (Trp-Trp) (interchain with W-33)","evidences":[{"source":"PubMed","id":"20600836","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---