4B90

Crystal structure of WT human CRMP-5

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004157	molecular_function	dihydropyrimidinase activity
A	0005515	molecular_function	protein binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006208	biological_process	pyrimidine nucleobase catabolic process
A	0007165	biological_process	signal transduction
A	0007399	biological_process	nervous system development
A	0007411	biological_process	axon guidance
A	0016787	molecular_function	hydrolase activity
A	0016810	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
A	0016812	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
A	0030182	biological_process	neuron differentiation
A	0030425	cellular_component	dendrite
A	0032991	cellular_component	protein-containing complex
A	0043025	cellular_component	neuronal cell body
A	0045202	cellular_component	synapse
A	0050774	biological_process	negative regulation of dendrite morphogenesis
A	0098978	cellular_component	glutamatergic synapse
B	0004157	molecular_function	dihydropyrimidinase activity
B	0005515	molecular_function	protein binding
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006208	biological_process	pyrimidine nucleobase catabolic process
B	0007165	biological_process	signal transduction
B	0007399	biological_process	nervous system development
B	0007411	biological_process	axon guidance
B	0016787	molecular_function	hydrolase activity
B	0016810	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
B	0016812	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
B	0030182	biological_process	neuron differentiation
B	0030425	cellular_component	dendrite
B	0032991	cellular_component	protein-containing complex
B	0043025	cellular_component	neuronal cell body
B	0045202	cellular_component	synapse
B	0050774	biological_process	negative regulation of dendrite morphogenesis
B	0098978	cellular_component	glutamatergic synapse

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO A 1492

Chain	Residue
A	GLN36
A	GLN37
A	VAL38
A	PRO396

---

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO B 1493

Chain	Residue
B	ASP20
B	ASN371
B	ARG372
B	ALA375
B	HOH2060

---