4B7W

Ligand binding domain human hepatocyte nuclear factor 4alpha: Apo form

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003323	biological_process	type B pancreatic cell development
A	0003700	molecular_function	DNA-binding transcription factor activity
A	0050796	biological_process	regulation of insulin secretion
A	0055088	biological_process	lipid homeostasis
A	0070365	biological_process	hepatocyte differentiation
B	0003323	biological_process	type B pancreatic cell development
B	0003700	molecular_function	DNA-binding transcription factor activity
B	0050796	biological_process	regulation of insulin secretion
B	0055088	biological_process	lipid homeostasis
B	0070365	biological_process	hepatocyte differentiation
C	0003323	biological_process	type B pancreatic cell development
C	0003700	molecular_function	DNA-binding transcription factor activity
C	0050796	biological_process	regulation of insulin secretion
C	0055088	biological_process	lipid homeostasis
C	0070365	biological_process	hepatocyte differentiation
D	0003323	biological_process	type B pancreatic cell development
D	0003700	molecular_function	DNA-binding transcription factor activity
D	0050796	biological_process	regulation of insulin secretion
D	0055088	biological_process	lipid homeostasis
D	0070365	biological_process	hepatocyte differentiation

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	32
Details	Motif: {"description":"9aaTAD","evidences":[{"source":"PubMed","id":"30468856","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	4
Details	Modified residue: {"description":"Phosphoserine; by AMPK","evidences":[{"source":"PubMed","id":"12740371","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	12
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"21708125","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details