4B5M

Neisseria AP endonuclease bound to the substrate with a cytosine orphan base

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0003824	molecular_function	catalytic activity
A	0003906	molecular_function	DNA-(apurinic or apyrimidinic site) endonuclease activity
A	0004518	molecular_function	nuclease activity
A	0004519	molecular_function	endonuclease activity
A	0006281	biological_process	DNA repair
A	0006284	biological_process	base-excision repair
A	0008081	molecular_function	phosphoric diester hydrolase activity
A	0008311	molecular_function	double-stranded DNA 3'-5' DNA exonuclease activity
A	0016787	molecular_function	hydrolase activity
A	0046872	molecular_function	metal ion binding
B	0003677	molecular_function	DNA binding
B	0003824	molecular_function	catalytic activity
B	0003906	molecular_function	DNA-(apurinic or apyrimidinic site) endonuclease activity
B	0004518	molecular_function	nuclease activity
B	0004519	molecular_function	endonuclease activity
B	0006281	biological_process	DNA repair
B	0006284	biological_process	base-excision repair
B	0008081	molecular_function	phosphoric diester hydrolase activity
B	0008311	molecular_function	double-stranded DNA 3'-5' DNA exonuclease activity
B	0016787	molecular_function	hydrolase activity
B	0046872	molecular_function	metal ion binding
C	0003677	molecular_function	DNA binding
C	0003824	molecular_function	catalytic activity
C	0003906	molecular_function	DNA-(apurinic or apyrimidinic site) endonuclease activity
C	0004518	molecular_function	nuclease activity
C	0004519	molecular_function	endonuclease activity
C	0006281	biological_process	DNA repair
C	0006284	biological_process	base-excision repair
C	0008081	molecular_function	phosphoric diester hydrolase activity
C	0008311	molecular_function	double-stranded DNA 3'-5' DNA exonuclease activity
C	0016787	molecular_function	hydrolase activity
C	0046872	molecular_function	metal ion binding

Functional Information from PROSITE/UniProt

site_id	PS00726
Number of Residues	10
Details	AP_NUCLEASE_F1_1 AP endonucleases family 1 signature 1. ADIVCVQELK

Chain	Residue	Details
A	ALA29-LYS38

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