4B2A
Structure of the factor Xa-like trypsin variant triple-Ala (TGA) in complex with eglin C
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004175 | molecular_function | endopeptidase activity |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005615 | cellular_component | extracellular space |
| A | 0006508 | biological_process | proteolysis |
| A | 0007586 | biological_process | digestion |
| A | 0008236 | molecular_function | serine-type peptidase activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0097180 | cellular_component | serine protease inhibitor complex |
| A | 0097655 | molecular_function | serpin family protein binding |
| B | 0004867 | molecular_function | serine-type endopeptidase inhibitor activity |
| B | 0009611 | biological_process | response to wounding |
| C | 0004175 | molecular_function | endopeptidase activity |
| C | 0004252 | molecular_function | serine-type endopeptidase activity |
| C | 0005515 | molecular_function | protein binding |
| C | 0005576 | cellular_component | extracellular region |
| C | 0005615 | cellular_component | extracellular space |
| C | 0006508 | biological_process | proteolysis |
| C | 0007586 | biological_process | digestion |
| C | 0008236 | molecular_function | serine-type peptidase activity |
| C | 0046872 | molecular_function | metal ion binding |
| C | 0097180 | cellular_component | serine protease inhibitor complex |
| C | 0097655 | molecular_function | serpin family protein binding |
| D | 0004867 | molecular_function | serine-type endopeptidase inhibitor activity |
| D | 0009611 | biological_process | response to wounding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 1246 |
| Chain | Residue |
| A | GLU70 |
| A | ASN72 |
| A | VAL75 |
| A | GLU80 |
| A | HOH2026 |
| A | HOH2027 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA C 1246 |
| Chain | Residue |
| C | GLU80 |
| C | HOH2023 |
| C | HOH2024 |
| C | GLU70 |
| C | ASN72 |
| C | VAL75 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL C 1247 |
| Chain | Residue |
| C | ASN34 |
| C | GLY38 |
| C | TYR39 |
| C | HIS40 |
| C | ARG66 |
| C | ASN74 |
| C | HOH2025 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A 1247 |
| Chain | Residue |
| A | ASN34 |
| A | GLY38 |
| A | TYR39 |
| A | HIS40 |
| A | ARG66 |
| A | ILE73 |
| A | ASN74 |
| A | HOH2030 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL B 1071 |
| Chain | Residue |
| A | HOH2064 |
| B | GLU39 |
| B | GLY40 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO B 1072 |
| Chain | Residue |
| B | ASP33 |
| B | VAL34 |
| B | HOH2005 |
Functional Information from PROSITE/UniProt
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | SITE: Reactive bond |
| Chain | Residue | Details |
| B | LYS45 | |
| D | LYS45 | |
| A | ALA195 | |
| C | HIS57 | |
| C | ASP102 | |
| C | ALA195 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 14 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | GLU70 | |
| C | VAL75 | |
| C | GLU80 | |
| C | ASP189 | |
| C | GLN192 | |
| C | ALA195 | |
| A | ASN72 | |
| A | VAL75 | |
| A | GLU80 | |
| A | ASP189 | |
| A | GLN192 | |
| A | ALA195 | |
| C | GLU70 | |
| C | ASN72 |
