Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004672 | molecular_function | protein kinase activity |
A | 0005524 | molecular_function | ATP binding |
A | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 13 |
Details | BINDING SITE FOR RESIDUE AMP A 1474 |
Chain | Residue |
A | GLN226 |
A | LEU315 |
A | MET358 |
A | ILE368 |
A | HOH2187 |
A | PRO229 |
A | TYR243 |
A | PHE245 |
A | VAL250 |
A | MET308 |
A | GLU309 |
A | LYS310 |
A | LEU311 |
site_id | AC2 |
Number of Residues | 18 |
Details | BINDING SITE FOR RESIDUE SAM A 1475 |
Chain | Residue |
A | TYR16 |
A | GLN17 |
A | ARG36 |
A | GLY61 |
A | ALA63 |
A | PHE67 |
A | ASP82 |
A | PHE83 |
A | GLN84 |
A | ASN87 |
A | GLY108 |
A | ARG109 |
A | ILE110 |
A | GLU111 |
A | LEU128 |
A | SER129 |
A | VAL130 |
A | HOH2058 |
site_id | AC3 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE SO4 A 1476 |
Chain | Residue |
A | ARG31 |
A | ASP32 |
A | CYS33 |
A | ASN34 |
A | GLN35 |
A | ARG36 |
A | HOH2036 |
A | HOH2038 |
site_id | AC4 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE SO4 A 1477 |
Chain | Residue |
A | ALA50 |
A | ARG212 |
A | PRO221 |
site_id | AC5 |
Number of Residues | 1 |
Details | BINDING SITE FOR RESIDUE SO4 A 1478 |
site_id | AC6 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE SO4 A 1479 |
Chain | Residue |
A | ARG92 |
A | ARG106 |
A | VAL107 |
site_id | AC7 |
Number of Residues | 9 |
Details | BINDING SITE FOR RESIDUE SO4 A 1480 |
Chain | Residue |
A | PRO167 |
A | PRO167 |
A | PRO167 |
A | PHE168 |
A | PHE168 |
A | PHE168 |
A | TYR169 |
A | TYR169 |
A | TYR169 |
site_id | AC8 |
Number of Residues | 9 |
Details | BINDING SITE FOR RESIDUE SO4 A 1481 |
Chain | Residue |
A | ARG179 |
A | TYR188 |
A | LEU190 |
A | TYR206 |
A | TYR255 |
A | ASP257 |
A | GLN302 |
A | HOH2120 |
A | HOH2121 |
site_id | AC9 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE SO4 A 1482 |
Chain | Residue |
A | GLN223 |
A | HIS224 |
A | PHE245 |
A | LYS310 |
site_id | BC1 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE SO4 A 1483 |
Chain | Residue |
A | ILE326 |
A | ASP327 |
A | ARG328 |
A | GLU329 |
A | TRP422 |
site_id | BC2 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE SO4 A 1484 |
Chain | Residue |
A | SER334 |
A | ARG337 |
A | HIS364 |
site_id | BC3 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE SO4 A 1485 |
Chain | Residue |
A | ARG92 |
A | ALA103 |
A | GLU104 |
A | PHE105 |
A | ARG106 |
site_id | BC4 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE SO4 A 1486 |
Chain | Residue |
A | ASN300 |
A | ALA301 |
A | LYS451 |
A | HOH2157 |
A | HOH2185 |
site_id | BC5 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE CL A 1487 |
Chain | Residue |
A | VAL130 |
A | PHE131 |
A | HIS132 |
A | GLU160 |
A | LEU161 |
A | ALA162 |
A | HOH2094 |
site_id | BC6 |
Number of Residues | 2 |
Details | BINDING SITE FOR RESIDUE CL A 1488 |
Chain | Residue |
A | GLU142 |
A | ARG145 |
Functional Information from PROSITE/UniProt
site_id | PS00109 |
Number of Residues | 13 |
Details | PROTEIN_KINASE_TYR Tyrosine protein kinases specific active-site signature. FWHdDVRPWNVMV |
Chain | Residue | Details |
A | PHE347-VAL359 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | TYR16 | |
A | LYS252 | |
A | GLU274 | |
A | GLU309 | |
A | MET358 | |
A | ASP369 | |
A | ARG36 | |
A | GLY61 | |
A | ASP82 | |
A | GLY108 | |
A | LEU128 | |
A | PRO229 | |
A | HIS237 | |
A | ARG241 | |