4AYD

Structure of a complex between CCPs 6 and 7 of Human Complement Factor H and Neisseria meningitidis FHbp Variant 1 R106A mutant

Functional Information from GO Data

Chain	GOid	namespace	contents
C	0005515	molecular_function	protein binding
C	0005576	cellular_component	extracellular region
C	0009279	cellular_component	cell outer membrane
C	0097691	cellular_component	bacterial extracellular vesicle
D	0005515	molecular_function	protein binding
D	0005576	cellular_component	extracellular region
D	0009279	cellular_component	cell outer membrane
D	0097691	cellular_component	bacterial extracellular vesicle
F	0005515	molecular_function	protein binding
F	0005576	cellular_component	extracellular region
F	0009279	cellular_component	cell outer membrane
F	0097691	cellular_component	bacterial extracellular vesicle

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE EDO E 1444

Chain	Residue
E	ASP329
E	HOH2007
E	HOH2012

---

site_id	AC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE EDO D 1322

Chain	Residue
D	SER302
A	ARG341
A	TYR353
A	HOH2023
A	HOH2055
D	SER286
D	SER288

---

site_id	AC3
Number of Residues	8
Details	BINDING SITE FOR RESIDUE EDO F 1322

Chain	Residue
E	HIS337
E	ARG341
E	TYR353
E	HOH2052
F	SER286
F	SER288
F	SER302
F	HOH2127

---

site_id	AC4
Number of Residues	9
Details	BINDING SITE FOR RESIDUE EDO C 1323

Chain	Residue
B	HIS337
B	ARG341
B	TYR353
B	HOH2040
C	SER286
C	SER288
C	SER302
C	GLU304
C	HOH2144

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	186
Details	Domain: {"description":"Sushi 6","evidences":[{"source":"PROSITE-ProRule","id":"PRU00302","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	270
Details	Region: {"description":"Domain C","evidences":[{"source":"PubMed","id":"15664958","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	3
Details	Site: {"description":"Important for antibody recognition","evidences":[{"source":"PubMed","id":"15664958","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	126
Details	Region: {"description":"Domain B","evidences":[{"source":"PubMed","id":"15664958","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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