4AXV
Biochemical and structural characterization of the MpaA amidase as part of a conserved scavenging pathway for peptidoglycan derived peptides in gamma-proteobacteria
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004040 | molecular_function | amidase activity |
| A | 0004180 | molecular_function | carboxypeptidase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006508 | biological_process | proteolysis |
| A | 0008237 | molecular_function | metallopeptidase activity |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0009253 | biological_process | peptidoglycan catabolic process |
| A | 0016788 | molecular_function | hydrolase activity, acting on ester bonds |
| A | 0016998 | biological_process | cell wall macromolecule catabolic process |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0061473 | molecular_function | murein tripeptide carboxypeptidase activity |
| A | 0071555 | biological_process | cell wall organization |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 301 |
| Chain | Residue |
| A | HIS48 |
| A | GLU51 |
| A | HIS156 |
| A | HOH2017 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 302 |
| Chain | Residue |
| A | HOH2003 |
| A | PHE12 |
| A | LEU13 |
| A | ILE14 |
| A | LEU62 |
| A | LEU65 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | ACT_SITE: Proton donor/acceptor => ECO:0000255|PROSITE-ProRule:PRU01379 |
| Chain | Residue | Details |
| A | GLU209 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU01379, ECO:0000269|PubMed:22970852, ECO:0007744|PDB:4AXV |
| Chain | Residue | Details |
| A | HIS48 | |
| A | GLU51 | |
| A | HIS156 |
