4AXK

CRYSTAL STRUCTURE OF subHisA from the thermophile Corynebacterium efficiens

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000105	biological_process	L-histidine biosynthetic process
A	0000162	biological_process	L-tryptophan biosynthetic process
A	0003949	molecular_function	1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity
A	0004640	molecular_function	phosphoribosylanthranilate isomerase activity
A	0005737	cellular_component	cytoplasm
A	0008652	biological_process	amino acid biosynthetic process
A	0016853	molecular_function	isomerase activity
B	0000105	biological_process	L-histidine biosynthetic process
B	0000162	biological_process	L-tryptophan biosynthetic process
B	0003949	molecular_function	1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity
B	0004640	molecular_function	phosphoribosylanthranilate isomerase activity
B	0005737	cellular_component	cytoplasm
B	0008652	biological_process	amino acid biosynthetic process
B	0016853	molecular_function	isomerase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL A 1249

Chain	Residue
A	ASP52
A	ALA55
A	SER61
A	HIS63
A	GLY81
A	ARG91

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site_id	AC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL B 1251

Chain	Residue
B	HIS63
B	GLY81
B	GLY82
B	ARG91
B	ASP52
B	ALA55
B	SER61

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Active site: {"description":"Proton acceptor","evidences":[{"source":"HAMAP-Rule","id":"MF_01014","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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