Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006508 | biological_process | proteolysis |
| A | 0008236 | molecular_function | serine-type peptidase activity |
| A | 0070012 | molecular_function | oligopeptidase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 1711 |
| Chain | Residue |
| A | ALA226 |
| A | GLU227 |
| A | PHE228 |
| A | ILE276 |
| A | LYS281 |
| A | HOH2765 |
| A | HOH2766 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GOL A 1712 |
| Chain | Residue |
| A | PHE571 |
| A | ILE628 |
| A | GLN629 |
| A | PRO631 |
| A | ASN668 |
| A | HOH2667 |
| A | HOH2740 |
| A | PRO568 |
| A | ASP569 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A 1713 |
| Chain | Residue |
| A | GLU239 |
| A | ASP291 |
| A | TYR292 |
| A | HOH2370 |
| A | HOH2372 |
| A | HOH2441 |
| A | HOH2442 |
| A | HOH2444 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL A 1714 |
| Chain | Residue |
| A | VAL341 |
| A | HOH2503 |
| A | HOH2545 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 1715 |
| Chain | Residue |
| A | ASP8 |
| A | GLN38 |
| A | PHE42 |
| A | LYS183 |
| A | HOH2022 |
| A | HOH2767 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 1716 |
| Chain | Residue |
| A | LYS546 |
| A | GLY572 |
| A | SER632 |
| A | ASN668 |
| A | CYS703 |
| A | HOH2740 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 1717 |
| Chain | Residue |
| A | ARG85 |
| A | ASP104 |
| A | ARG111 |
| A | VAL158 |
| A | GLY160 |
| A | HOH2159 |
| A | HOH2198 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL A 1718 |
| Chain | Residue |
| A | ARG170 |
| A | TYR190 |
| A | TYR211 |
| A | GLN219 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL A 1719 |
| Chain | Residue |
| A | ARG11 |
| A | CYS25 |
| A | PRO27 |
| A | HOH2732 |
Functional Information from PROSITE/UniProt
| site_id | PS00708 |
| Number of Residues | 31 |
| Details | PRO_ENDOPEP_SER Prolyl endopeptidase family serine active site. DfqcAaeyLikegytspkrltinGgSnGGLL |
| Chain | Residue | Details |
| A | ASP529-LEU559 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | SER554 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | ACT_SITE: Charge relay system |
| Chain | Residue | Details |
| A | ASP641 | |
| Chain | Residue | Details |
| A | ALA680 | |
| Chain | Residue | Details |
| A | LYS157 | |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 4 |
| Details | M-CSA 901 |
| Chain | Residue | Details |
| A | TYR473 | electrostatic stabiliser |
| A | SER554 | covalent catalysis, proton shuttle (general acid/base) |
| A | ASP641 | electrostatic stabiliser, modifies pKa |
| A | ALA680 | proton shuttle (general acid/base) |
