4ATN

Crystal structure of C2498 2'-O-ribose methyltransferase RlmM from Escherichia coli

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005737	cellular_component	cytoplasm
A	0006364	biological_process	rRNA processing
A	0008168	molecular_function	methyltransferase activity
A	0008757	molecular_function	S-adenosylmethionine-dependent methyltransferase activity
A	0016740	molecular_function	transferase activity
A	0031167	biological_process	rRNA methylation
A	0032259	biological_process	methylation
A	0070677	molecular_function	rRNA (cytosine-2'-O-)-methyltransferase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL A 1358

Chain	Residue
A	ARG34
A	LYS36
A	TYR41
A	VAL42
A	ILE43
A	HOH2035

---

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL A 1359

Chain	Residue
A	GLN253
A	HOH2147
A	HOH2189
A	ARG85
A	ASN211
A	ASN233

---

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL A 1360

Chain	Residue
A	VAL96
A	VAL97
A	GLU98
A	ARG145
A	PRO146
A	TYR164

---

site_id	AC4
Number of Residues	10
Details	BINDING SITE FOR RESIDUE GOL A 1361

Chain	Residue
A	SER62
A	SER63
A	ILE65
A	LEU320
A	GLN337
A	ALA338
A	EDO1375
A	HOH2026
A	HOH2190
A	HOH2191

---

site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL A 1362

Chain	Residue
A	PHE171
A	PRO176
A	ARG177
A	HOH2110

---

site_id	AC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE EDO A 1363

Chain	Residue
A	PHE264
A	THR267
A	ARG268

---

site_id	AC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO A 1364

Chain	Residue
A	PHE61
A	SER62
A	ASN167
A	EDO1373

---

site_id	AC8
Number of Residues	8
Details	BINDING SITE FOR RESIDUE EDO A 1365

Chain	Residue
A	THR110
A	ASN111
A	GLU112
A	PRO222
A	PRO243
A	HOH2041
A	HOH2088
A	HOH2150

---

site_id	AC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO A 1366

Chain	Residue
A	ASP109
A	LYS114
A	HOH2085
A	HOH2192

---

site_id	BC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO A 1367

Chain	Residue
A	THR21
A	PHE32
A	ALA33
A	HOH2017
A	HOH2193

---

site_id	BC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO A 1368

Chain	Residue
A	LYS281
A	PRO308
A	MET309
A	LYS310

---

site_id	BC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO A 1369

Chain	Residue
A	ALA18
A	TYR313
A	GLU314
A	HOH2018

---

site_id	BC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE EDO A 1370

Chain	Residue
A	ARG34
A	VAL35
A	EDO1371

---

site_id	BC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO A 1371

Chain	Residue
A	ARG34
A	GLU259
A	ASP260
A	EDO1370

---

site_id	BC6
Number of Residues	7
Details	BINDING SITE FOR RESIDUE EDO A 1372

Chain	Residue
A	GLN48
A	PRO49
A	ASP50
A	ASP51
A	HIS330
A	HOH2046
A	HOH2047

---

site_id	BC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO A 1373

Chain	Residue
A	ARG57
A	ASN167
A	EDO1364
A	EDO1376

---

site_id	BC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE EDO A 1374

Chain	Residue
A	ASP22
A	HOH2171

---

site_id	BC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO A 1375

Chain	Residue
A	SER62
A	SER63
A	ILE336
A	GOL1361
A	HOH2194
A	HOH2195

---

site_id	CC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO A 1376

Chain	Residue
A	ARG57
A	ASN166
A	ASN167
A	EDO1373

---

site_id	CC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE EDO A 1377

Chain	Residue
A	GLY91
A	MET92
A	HOH2065

---

site_id	CC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO A 1378

Chain	Residue
A	ASP133
A	GLY135
A	TYR140
A	LYS99
A	ARG132

---

site_id	CC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO A 1379

Chain	Residue
A	PRO82
A	ARG85
A	VAL230
A	ASN233
A	GLN253

---

site_id	CC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO A 1380

Chain	Residue
A	SER269
A	ILE271
A	GLY296
A	TRP356

---

site_id	CC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO A 1381

Chain	Residue
A	ILE332
A	ASN333
A	ARG354
A	ILE355

---

site_id	CC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO A 1382

Chain	Residue
A	ARG187
A	HIS343
A	SO41387
A	HOH2122

---

site_id	CC8
Number of Residues	1
Details	BINDING SITE FOR RESIDUE EDO A 1383

Chain	Residue
A	ASP206

---

site_id	CC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 A 1384

Chain	Residue
A	LYS99
A	ALA138
A	ALA138
A	ASN139
A	ASN139
A	TYR140

---

site_id	DC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 A 1385

Chain	Residue
A	LYS118
A	ARG121
A	LYS122
A	SO41386

---

site_id	DC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 A 1386

Chain	Residue
A	ARG121
A	LYS122
A	TRP214
A	ARG268
A	ASN270
A	SO41385

---

site_id	DC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 A 1387

Chain	Residue
A	ARG187
A	SER188
A	LYS191
A	ARG345
A	EDO1382
A	HOH2122

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Active site: {"description":"Proton acceptor","evidences":[{"source":"PubMed","id":"22923526","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22923526","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	3
Details	Binding site: {}

Chain

Residue

Details

---