4ARC

Ternary complex of E. coli leucyl-tRNA synthetase, tRNA(leu) and leucine in the editing conformation

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0002161	molecular_function	aminoacyl-tRNA editing activity
A	0004812	molecular_function	aminoacyl-tRNA ligase activity
A	0004823	molecular_function	leucine-tRNA ligase activity
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006412	biological_process	translation
A	0006418	biological_process	tRNA aminoacylation for protein translation
A	0006429	biological_process	leucyl-tRNA aminoacylation
A	0106074	biological_process	aminoacyl-tRNA metabolism involved in translational fidelity

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE LEU A 1001

Chain	Residue
A	LEU41
A	TYR43
A	ASP80
A	HIS533
A	HIS537
A	HOH2050
A	HOH2053

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site_id	AC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG B 1077

Chain	Residue
B	U8
B	G9

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Functional Information from PROSITE/UniProt

site_id	PS00178
Number of Residues	12
Details	AA_TRNA_LIGASE_I Aminoacyl-transfer RNA synthetases class-I signature. PypSGrLHMGHV

Chain	Residue	Details
A	PRO42-VAL53

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00049

Chain	Residue	Details
A	LYS622

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