4AP5
Crystal structure of human POFUT2
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005783 | cellular_component | endoplasmic reticulum |
| A | 0005789 | cellular_component | endoplasmic reticulum membrane |
| A | 0005794 | cellular_component | Golgi apparatus |
| A | 0008417 | molecular_function | fucosyltransferase activity |
| A | 0036066 | biological_process | protein O-linked glycosylation via fucose |
| A | 0046922 | molecular_function | peptide-O-fucosyltransferase activity |
| A | 0051046 | biological_process | regulation of secretion |
| A | 1903334 | biological_process | positive regulation of protein folding |
| B | 0005783 | cellular_component | endoplasmic reticulum |
| B | 0005789 | cellular_component | endoplasmic reticulum membrane |
| B | 0005794 | cellular_component | Golgi apparatus |
| B | 0008417 | molecular_function | fucosyltransferase activity |
| B | 0036066 | biological_process | protein O-linked glycosylation via fucose |
| B | 0046922 | molecular_function | peptide-O-fucosyltransferase activity |
| B | 0051046 | biological_process | regulation of secretion |
| B | 1903334 | biological_process | positive regulation of protein folding |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PubMed","id":"22588082","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 16 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"22588082","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4AP6","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Site: {"description":"Essential for catalytic activity","evidences":[{"source":"PubMed","id":"17395589","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22588082","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"22588082","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
