4AP5

Crystal structure of human POFUT2

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005783	cellular_component	endoplasmic reticulum
A	0005789	cellular_component	endoplasmic reticulum membrane
A	0005794	cellular_component	Golgi apparatus
A	0006004	biological_process	fucose metabolic process
A	0006486	biological_process	obsolete protein glycosylation
A	0008417	molecular_function	fucosyltransferase activity
A	0016740	molecular_function	transferase activity
A	0016757	molecular_function	glycosyltransferase activity
A	0036066	biological_process	protein O-linked glycosylation via fucose
A	0046922	molecular_function	peptide-O-fucosyltransferase activity
A	0051046	biological_process	regulation of secretion
A	1903334	biological_process	positive regulation of protein folding
B	0005783	cellular_component	endoplasmic reticulum
B	0005789	cellular_component	endoplasmic reticulum membrane
B	0005794	cellular_component	Golgi apparatus
B	0006004	biological_process	fucose metabolic process
B	0006486	biological_process	obsolete protein glycosylation
B	0008417	molecular_function	fucosyltransferase activity
B	0016740	molecular_function	transferase activity
B	0016757	molecular_function	glycosyltransferase activity
B	0036066	biological_process	protein O-linked glycosylation via fucose
B	0046922	molecular_function	peptide-O-fucosyltransferase activity
B	0051046	biological_process	regulation of secretion
B	1903334	biological_process	positive regulation of protein folding

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Active site: {"description":"Proton acceptor","evidences":[{"source":"PubMed","id":"22588082","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	16
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22588082","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4AP6","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	2
Details	Site: {"description":"Essential for catalytic activity","evidences":[{"source":"PubMed","id":"17395589","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22588082","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	4
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"22588082","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	2
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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