4AIF
AIP TPR domain in complex with human Hsp90 peptide
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1316 |
| Chain | Residue |
| A | ARG304 |
| A | GLN307 |
| A | HOH2142 |
| B | GLN307 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 66 |
| Details | Repeat: {"description":"TPR 1","evidences":[{"evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"23300914","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 66 |
| Details | Repeat: {"description":"TPR 2","evidences":[{"source":"PubMed","id":"23300914","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 66 |
| Details | Repeat: {"description":"TPR 3","evidences":[{"evidenceCode":"ECO:0000255"},{"source":"PROSITE-ProRule","id":"PRU00339","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"23300914","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 8 |
| Details | Region: {"description":"Essential for interaction with SMYD3, TSC1 and STIP1/HOP","evidences":[{"source":"PubMed","id":"25738358","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"29127155","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 6 |
| Details | Region: {"description":"Essential for interaction with SGTA and TTC1","evidences":[{"source":"PubMed","id":"15708368","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
