Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004197 | molecular_function | cysteine-type endopeptidase activity |
| A | 0005634 | cellular_component | nucleus |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005768 | cellular_component | endosome |
| A | 0006508 | biological_process | proteolysis |
| A | 0008234 | molecular_function | cysteine-type peptidase activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0055037 | cellular_component | recycling endosome |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NA A 1348 |
| Chain | Residue |
| A | LEU23 |
| A | GLN98 |
| A | HOH2115 |
| A | HOH2240 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE NA A 1349 |
| Chain | Residue |
| A | GLN29 |
| A | LYS314 |
| A | ARG315 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE NA A 1350 |
| Chain | Residue |
| A | HOH2170 |
| A | SER198 |
| A | ASP247 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CL A 1351 |
| Chain | Residue |
| A | LYS163 |
| A | HIS238 |
| A | ASP329 |
| A | HOH2214 |
| A | HOH2276 |
| A | HOH2288 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA A 1352 |
| Chain | Residue |
| A | GLN34 |
| A | LEU36 |
| A | HIS158 |
| A | GLY159 |
| A | HOH2149 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL A 1353 |
| Chain | Residue |
| A | LEU68 |
| A | GLN71 |
| A | HOH2122 |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | HIS158 | |
| Chain | Residue | Details |
| A | GLY213 | |
| Chain | Residue | Details |
| A | ASP173 | |
| A | ASP189 | |
| A | ASP190 | |
| A | ASP220 | |
| Chain | Residue | Details |
| A | LYS55 | |
| A | LYS268 | |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | SITE: Important for Arg/Lys-specific substrate specificity => ECO:0000269|PubMed:22529389 |
| Chain | Residue | Details |
| A | ASP95 | |
| A | ASP211 | |
