4ADT
Crystal structure of plasmodial PLP synthase
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0006520 | biological_process | amino acid metabolic process |
| A | 0008615 | biological_process | pyridoxine biosynthetic process |
| A | 0016829 | molecular_function | lyase activity |
| A | 0016843 | molecular_function | amine-lyase activity |
| A | 0036381 | molecular_function | pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity |
| A | 0042819 | biological_process | vitamin B6 biosynthetic process |
| A | 0042823 | biological_process | pyridoxal phosphate biosynthetic process |
| B | 0006520 | biological_process | amino acid metabolic process |
| B | 0008615 | biological_process | pyridoxine biosynthetic process |
| B | 0016829 | molecular_function | lyase activity |
| B | 0016843 | molecular_function | amine-lyase activity |
| B | 0036381 | molecular_function | pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity |
| B | 0042819 | biological_process | vitamin B6 biosynthetic process |
| B | 0042823 | biological_process | pyridoxal phosphate biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PO4 A 301 |
| Chain | Residue |
| A | HIS118 |
| A | ARG140 |
| A | ARG141 |
| A | LYS190 |
| A | HOH2057 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE PO4 A 302 |
| Chain | Residue |
| A | GLY238 |
| A | SER239 |
| A | HOH2040 |
| A | HOH2051 |
| A | GLY156 |
| A | GLY216 |
| A | GLY217 |
| A | VAL237 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PO4 B 301 |
| Chain | Residue |
| B | HIS118 |
| B | ARG140 |
| B | ARG141 |
| B | LYS190 |
| B | HOH2039 |
| B | HOH2041 |
| site_id | AC4 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE PO4 B 302 |
| Chain | Residue |
| B | ALA155 |
| B | GLY156 |
| B | GLY216 |
| B | GLY217 |
| B | GLY238 |
| B | SER239 |
| B | HOH2033 |
| B | HOH2044 |
| B | HOH2045 |
Functional Information from PROSITE/UniProt
| site_id | PS01235 |
| Number of Residues | 19 |
| Details | PDXS_SNZ_1 PdxS/SNZ family signature. LPVVNFAAGGIATPADAAM |
| Chain | Residue | Details |
| A | LEU208-MET226 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Schiff-base intermediate with D-ribose 5-phosphate","evidences":[{"source":"PubMed","id":"22244765","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"22244765","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"Q03148","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
