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4A9K

BROMODOMAIN OF HUMAN CREBBP WITH N-(4-hydroxyphenyl)acetamide

Functional Information from GO Data
ChainGOidnamespacecontents
A0004402molecular_functionhistone acetyltransferase activity
A0006355biological_processregulation of DNA-templated transcription
B0004402molecular_functionhistone acetyltransferase activity
B0006355biological_processregulation of DNA-templated transcription
Functional Information from PDB Data
site_idAC1
Number of Residues2
DetailsBINDING SITE FOR RESIDUE EDO A 2198
ChainResidue
ATRP1165
ATYR1175

site_idAC2
Number of Residues6
DetailsBINDING SITE FOR RESIDUE EDO A 2199
ChainResidue
APRO1117
AGLN1118
AGLY1121
AILE1122
APRO1123
AHOH2148

site_idAC3
Number of Residues6
DetailsBINDING SITE FOR RESIDUE K B 2197
ChainResidue
BLEU1166
BASN1168
BHOH2011
BHOH2012
BHOH2098
BTRP1165

site_idAC4
Number of Residues10
DetailsBINDING SITE FOR RESIDUE TYL A 2200
ChainResidue
APHE1111
AVAL1115
AILE1122
ATYR1167
AASN1168
AVAL1174
AHOH2051
AHOH2067
AHOH2149
AHOH2150

site_idAC5
Number of Residues6
DetailsBINDING SITE FOR RESIDUE TYL B 2198
ChainResidue
BVAL1115
BASN1168
BVAL1174
BHOH2040
BHOH2058
BHOH2117

site_idAC6
Number of Residues4
DetailsBINDING SITE FOR RESIDUE SCN A 2201
ChainResidue
AARG1173
AHOH2126
BPRO1106
BARG1173

Functional Information from PROSITE/UniProt
site_idPS00633
Number of Residues60
DetailsBROMODOMAIN_1 Bromodomain signature. SlpFrqpvDpqllgipDYFdiVknpMdlstIkrkldtgq..Yqepwqyvddvwl.MfnNAwlY
ChainResidueDetails
ASER1108-TYR1167

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PDB entries from 2024-11-06

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