4A9F
N-TERMINAL BROMODOMAIN OF HUMAN BRD2 WITH 1-METHYLPYRROLIDIN-2-ONE
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO B 1186 |
| Chain | Residue |
| B | ARG128 |
| B | ARG129 |
| B | HOH2077 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MB3 A 1183 |
| Chain | Residue |
| A | PHE99 |
| A | VAL103 |
| A | LEU108 |
| A | ASN156 |
| A | HOH2079 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MB3 B 1187 |
| Chain | Residue |
| B | VAL103 |
| B | ASN156 |
| B | HOH2051 |
| B | PHE99 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MB3 C 1183 |
| Chain | Residue |
| C | VAL103 |
| C | LEU108 |
| C | ASN156 |
| C | HOH2045 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 C 1184 |
| Chain | Residue |
| B | ARG100 |
| C | ARG128 |
| C | ASN132 |
| C | TYR134 |
| C | HOH2068 |
| C | HOH2112 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1184 |
| Chain | Residue |
| A | ARG100 |
| A | HOH2021 |
| A | HOH2024 |
| A | HOH2200 |
| A | HOH2202 |
Functional Information from PROSITE/UniProt
| site_id | PS00633 |
| Number of Residues | 60 |
| Details | BROMODOMAIN_1 Bromodomain signature. AwpFrqpvDavklglpDYHkiIkqpMdmgtIkrrlenny..Ywaasecmqdfnt.MftNCyiY |
| Chain | Residue | Details |
| A | ALA96-TYR155 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"37731000","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8SB6","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"20048151","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2DVQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2DVS","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
