4A90

Crystal structure of mouse SAP18 residues 1-143

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000118	cellular_component	histone deacetylase complex
A	0000381	biological_process	regulation of alternative mRNA splicing, via spliceosome
A	0003714	molecular_function	transcription corepressor activity
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005654	cellular_component	nucleoplasm
A	0005667	cellular_component	transcription regulator complex
A	0005737	cellular_component	cytoplasm
A	0006355	biological_process	regulation of DNA-templated transcription
A	0006397	biological_process	mRNA processing
A	0008380	biological_process	RNA splicing
A	0016607	cellular_component	nuclear speck
A	0043065	biological_process	positive regulation of apoptotic process
A	0045892	biological_process	negative regulation of DNA-templated transcription
A	0048025	biological_process	negative regulation of mRNA splicing, via spliceosome
A	0061574	cellular_component	ASAP complex
B	0000118	cellular_component	histone deacetylase complex
B	0000381	biological_process	regulation of alternative mRNA splicing, via spliceosome
B	0003714	molecular_function	transcription corepressor activity
B	0005515	molecular_function	protein binding
B	0005634	cellular_component	nucleus
B	0005654	cellular_component	nucleoplasm
B	0005667	cellular_component	transcription regulator complex
B	0005737	cellular_component	cytoplasm
B	0006355	biological_process	regulation of DNA-templated transcription
B	0006397	biological_process	mRNA processing
B	0008380	biological_process	RNA splicing
B	0016607	cellular_component	nuclear speck
B	0043065	biological_process	positive regulation of apoptotic process
B	0045892	biological_process	negative regulation of DNA-templated transcription
B	0048025	biological_process	negative regulation of mRNA splicing, via spliceosome
B	0061574	cellular_component	ASAP complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL A 1142

Chain	Residue
A	LEU29
A	ARG31
A	TYR132
B	GLN57

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site_id	AC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE GOL A 1143

Chain	Residue
A	LYS24

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	MOD_RES: N-acetylalanine => ECO:0000250|UniProtKB:O00422

Chain	Residue	Details
A	ALA2
B	ALA2

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site_id	SWS_FT_FI2
Number of Residues	4
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0000250|UniProtKB:O00422

Chain	Residue	Details
A	LYS13
B	LYS13

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