4A8S

Non-Catalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial dsRNA virus phi6 from De Novo Initiation to Elongation

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0001172	biological_process	RNA-templated transcription
A	0003723	molecular_function	RNA binding
A	0003968	molecular_function	RNA-dependent RNA polymerase activity
A	0006351	biological_process	DNA-templated transcription
A	0019079	biological_process	viral genome replication
A	0034062	molecular_function	5'-3' RNA polymerase activity
A	0039694	biological_process	viral RNA genome replication
A	0044423	cellular_component	virion component
A	0046872	molecular_function	metal ion binding
A	0050265	molecular_function	RNA uridylyltransferase activity
B	0000166	molecular_function	nucleotide binding
B	0001172	biological_process	RNA-templated transcription
B	0003723	molecular_function	RNA binding
B	0003968	molecular_function	RNA-dependent RNA polymerase activity
B	0006351	biological_process	DNA-templated transcription
B	0019079	biological_process	viral genome replication
B	0034062	molecular_function	5'-3' RNA polymerase activity
B	0039694	biological_process	viral RNA genome replication
B	0044423	cellular_component	virion component
B	0046872	molecular_function	metal ion binding
B	0050265	molecular_function	RNA uridylyltransferase activity
C	0000166	molecular_function	nucleotide binding
C	0001172	biological_process	RNA-templated transcription
C	0003723	molecular_function	RNA binding
C	0003968	molecular_function	RNA-dependent RNA polymerase activity
C	0006351	biological_process	DNA-templated transcription
C	0019079	biological_process	viral genome replication
C	0034062	molecular_function	5'-3' RNA polymerase activity
C	0039694	biological_process	viral RNA genome replication
C	0044423	cellular_component	virion component
C	0046872	molecular_function	metal ion binding
C	0050265	molecular_function	RNA uridylyltransferase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG A 1665

Chain	Residue
A	THR323
A	ASP454
A	ALA455
A	GLU491
A	ALA495

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site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE ATP A 1666

Chain	Residue
A	SER326
A	MG1667
A	LYS223
A	ARG225
A	ARG268
A	ARG270

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site_id	AC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG A 1667

Chain	Residue
A	ASP324
A	VAL325
A	ATP1666

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site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG B 1665

Chain	Residue
B	THR323
B	ASP454
B	GLU491
B	ALA495

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site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ATP B 1666

Chain	Residue
B	LYS223
B	ARG225
B	SER326
B	ASP327

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site_id	AC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE ATP C 1665

Chain	Residue
C	LYS223
C	ARG225
C	ASP324

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	9
Details	BINDING:

Chain	Residue	Details
A	ASP453
A	TYR490
C	ASP453
C	TYR490
C	GLY494
A	GLY494
B	ASP453
B	TYR490
B	GLY494

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