4A1Y

Human myelin P2 protein, K65Q mutant

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005504	molecular_function	fatty acid binding
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0008289	molecular_function	lipid binding
A	0015485	molecular_function	cholesterol binding
A	0015908	biological_process	fatty acid transport
A	0043209	cellular_component	myelin sheath
A	0061024	biological_process	membrane organization
A	0070062	cellular_component	extracellular exosome
B	0005504	molecular_function	fatty acid binding
B	0005515	molecular_function	protein binding
B	0005634	cellular_component	nucleus
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0008289	molecular_function	lipid binding
B	0015485	molecular_function	cholesterol binding
B	0015908	biological_process	fatty acid transport
B	0043209	cellular_component	myelin sheath
B	0061024	biological_process	membrane organization
B	0070062	cellular_component	extracellular exosome
C	0005504	molecular_function	fatty acid binding
C	0005515	molecular_function	protein binding
C	0005634	cellular_component	nucleus
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0008289	molecular_function	lipid binding
C	0015485	molecular_function	cholesterol binding
C	0015908	biological_process	fatty acid transport
C	0043209	cellular_component	myelin sheath
C	0061024	biological_process	membrane organization
C	0070062	cellular_component	extracellular exosome
D	0005504	molecular_function	fatty acid binding
D	0005515	molecular_function	protein binding
D	0005634	cellular_component	nucleus
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0008289	molecular_function	lipid binding
D	0015485	molecular_function	cholesterol binding
D	0015908	biological_process	fatty acid transport
D	0043209	cellular_component	myelin sheath
D	0061024	biological_process	membrane organization
D	0070062	cellular_component	extracellular exosome

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE PLM A 1132

Chain	Residue
A	SER55
A	ARG106
A	ARG126
A	TYR128
A	HOH1157
A	HOH1221

---

site_id	AC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL A 1133

Chain	Residue
A	LYS37
A	SER55
A	THR56

---

site_id	AC3
Number of Residues	8
Details	BINDING SITE FOR RESIDUE PLM B 1132

Chain	Residue
B	MET20
B	THR29
B	ASP76
B	ARG106
B	ARG126
B	TYR128
B	HOH1336
B	HOH1351

---

site_id	AC4
Number of Residues	7
Details	BINDING SITE FOR RESIDUE PLM C 1132

Chain	Residue
C	MET20
C	GLY33
C	ARG106
C	ARG126
C	TYR128
C	HOH1369
C	HOH1370

---

site_id	AC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL C 1133

Chain	Residue
C	LYS37
C	SER55
C	THR56

---

site_id	AC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL D 1132

Chain	Residue
D	LYS37
D	SER55
D	THR56

---

site_id	AC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE PLM D 1133

Chain	Residue
D	ASP76
D	ARG106
D	ARG126
D	TYR128
D	HOH1354
D	HOH1355

---

Functional Information from PROSITE/UniProt

site_id	PS00214
Number of Residues	18
Details	FABP Cytosolic fatty-acid binding proteins signature. GTWkLvsSeNFDdYMKAL

Chain	Residue	Details
A	GLY6-LEU23

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"PubMed","id":"20421974","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2WUT","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	Modified residue: {"description":"N-acetylserine","evidences":[{"source":"PubMed","id":"6183401","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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