4A0Z
Structure of the global transcription regulator FapR from Staphylococcus aureus in complex with malonyl-CoA
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0003677 | molecular_function | DNA binding |
A | 0003700 | molecular_function | DNA-binding transcription factor activity |
A | 0006633 | biological_process | fatty acid biosynthetic process |
A | 0045717 | biological_process | negative regulation of fatty acid biosynthetic process |
A | 0045892 | biological_process | negative regulation of DNA-templated transcription |
A | 0046872 | molecular_function | metal ion binding |
B | 0003677 | molecular_function | DNA binding |
B | 0003700 | molecular_function | DNA-binding transcription factor activity |
B | 0006633 | biological_process | fatty acid biosynthetic process |
B | 0045717 | biological_process | negative regulation of fatty acid biosynthetic process |
B | 0045892 | biological_process | negative regulation of DNA-templated transcription |
B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 24 |
Details | BINDING SITE FOR RESIDUE MLC A 201 |
Chain | Residue |
A | PHE103 |
A | HOH2060 |
A | HOH2071 |
A | HOH2097 |
A | HOH2098 |
A | HOH2099 |
B | ASN119 |
B | VAL123 |
B | THR130 |
B | LEU132 |
B | THR133 |
A | ALA109 |
B | HIS134 |
B | LYS162 |
B | PHE185 |
B | ASP187 |
B | ARG189 |
A | ARG110 |
A | GLY111 |
A | PHE140 |
A | ILE141 |
A | GLU142 |
A | LYS143 |
A | HOH2059 |
site_id | AC2 |
Number of Residues | 18 |
Details | BINDING SITE FOR RESIDUE MLC B 201 |
Chain | Residue |
A | ASN119 |
A | VAL123 |
A | THR133 |
A | HIS134 |
A | LYS162 |
A | PHE185 |
A | ASP187 |
A | HOH2062 |
B | PHE103 |
B | ALA109 |
B | ARG110 |
B | GLY111 |
B | PHE140 |
B | ILE141 |
B | GLU142 |
B | LYS143 |
B | HOH2027 |
B | HOH2051 |