4A0Z
Structure of the global transcription regulator FapR from Staphylococcus aureus in complex with malonyl-CoA
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003700 | molecular_function | DNA-binding transcription factor activity |
| A | 0045717 | biological_process | negative regulation of fatty acid biosynthetic process |
| A | 0045892 | biological_process | negative regulation of DNA-templated transcription |
| B | 0003700 | molecular_function | DNA-binding transcription factor activity |
| B | 0045717 | biological_process | negative regulation of fatty acid biosynthetic process |
| B | 0045892 | biological_process | negative regulation of DNA-templated transcription |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE MLC A 201 |
| Chain | Residue |
| A | PHE103 |
| A | HOH2060 |
| A | HOH2071 |
| A | HOH2097 |
| A | HOH2098 |
| A | HOH2099 |
| B | ASN119 |
| B | VAL123 |
| B | THR130 |
| B | LEU132 |
| B | THR133 |
| A | ALA109 |
| B | HIS134 |
| B | LYS162 |
| B | PHE185 |
| B | ASP187 |
| B | ARG189 |
| A | ARG110 |
| A | GLY111 |
| A | PHE140 |
| A | ILE141 |
| A | GLU142 |
| A | LYS143 |
| A | HOH2059 |
| site_id | AC2 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE MLC B 201 |
| Chain | Residue |
| A | ASN119 |
| A | VAL123 |
| A | THR133 |
| A | HIS134 |
| A | LYS162 |
| A | PHE185 |
| A | ASP187 |
| A | HOH2062 |
| B | PHE103 |
| B | ALA109 |
| B | ARG110 |
| B | GLY111 |
| B | PHE140 |
| B | ILE141 |
| B | GLU142 |
| B | LYS143 |
| B | HOH2027 |
| B | HOH2051 |
