43C9

CRYSTALLOGRAPHIC STRUCTURE OF THE ESTEROLYTIC AND AMIDOLYTIC 43C9 ANTIBODY

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	CATALYTIC SITE IS BELIEVED TO INCLUDE: HIS 91 IN THE VARIABLE LIGHT CHAIN - NUCLEOPHILE THAT FORMS A COVALENT BOND TO THE SUBSTRATE ARG 96 IN THE VARIABLE LIGHT CHAIN - SIDE CHAIN STABILIZES NEGATIVE CHARGE FORMED IN THE TRANSITION STATES OF THE REACTION

Chain	Residue
A	HIS91
A	ARG96

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site_id	AC2
Number of Residues	2
Details	CATALYTIC SITE IS BELIEVED TO INCLUDE: HIS 91 IN THE VARIABLE LIGHT CHAIN - NUCLEOPHILE THAT FORMS A COVALENT BOND TO THE SUBSTRATE ARG 96 IN THE VARIABLE LIGHT CHAIN - SIDE CHAIN STABILIZES NEGATIVE CHARGE FORMED IN THE TRANSITION STATES OF THE REACTION

Chain	Residue
C	HIS91
C	ARG96

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site_id	AC3
Number of Residues	2
Details	CATALYTIC SITE IS BELIEVED TO INCLUDE: HIS 91 IN THE VARIABLE LIGHT CHAIN - NUCLEOPHILE THAT FORMS A COVALENT BOND TO THE SUBSTRATE ARG 96 IN THE VARIABLE LIGHT CHAIN - SIDE CHAIN STABILIZES NEGATIVE CHARGE FORMED IN THE TRANSITION STATES OF THE REACTION

Chain	Residue
E	HIS91
E	ARG96

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site_id	AC4
Number of Residues	2
Details	CATALYTIC SITE IS BELIEVED TO INCLUDE: HIS 91 IN THE VARIABLE LIGHT CHAIN - NUCLEOPHILE THAT FORMS A COVALENT BOND TO THE SUBSTRATE ARG 96 IN THE VARIABLE LIGHT CHAIN - SIDE CHAIN STABILIZES NEGATIVE CHARGE FORMED IN THE TRANSITION STATES OF THE REACTION

Chain	Residue
G	HIS91
G	ARG96

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