3ZY5
Crystal structure of POFUT1 in complex with GDP-fucose (crystal-form-I)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005783 | cellular_component | endoplasmic reticulum |
| A | 0006004 | biological_process | fucose metabolic process |
| A | 0006486 | biological_process | obsolete protein glycosylation |
| A | 0007219 | biological_process | Notch signaling pathway |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016757 | molecular_function | glycosyltransferase activity |
| A | 0036066 | biological_process | protein O-linked glycosylation via fucose |
| A | 0046922 | molecular_function | peptide-O-fucosyltransferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1382 |
| Chain | Residue |
| A | CYS119 |
| A | TRP120 |
| A | THR121 |
| A | ARG123 |
| A | SER193 |
| A | SER194 |
| A | HOH2080 |
| A | HOH2081 |
| A | HOH2134 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1383 |
| Chain | Residue |
| A | HIS136 |
| A | SER137 |
| A | LYS138 |
| A | HOH2092 |
| A | HOH2094 |
| A | HOH2096 |
| A | HOH2109 |
| A | HOH2110 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1384 |
| Chain | Residue |
| A | MET172 |
| A | GLY173 |
| A | SER174 |
| A | ARG175 |
| A | LYS176 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1385 |
| Chain | Residue |
| A | GLN85 |
| A | VAL86 |
| A | GLY87 |
| A | HOH2048 |
| A | HOH2199 |
| site_id | AC5 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE GFB A 1386 |
| Chain | Residue |
| A | ARG40 |
| A | PHE41 |
| A | GLY42 |
| A | ASN43 |
| A | PRO133 |
| A | HIS238 |
| A | ARG240 |
| A | TRP245 |
| A | ALA307 |
| A | SER308 |
| A | ASP309 |
| A | ASP334 |
| A | MET336 |
| A | SER355 |
| A | THR356 |
| A | PHE357 |
| A | HOH2015 |
| A | HOH2016 |
| A | HOH2018 |
| site_id | AC6 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE BTB A 1387 |
| Chain | Residue |
| A | TRP120 |
| A | TRP120 |
| A | THR121 |
| A | TYR159 |
| A | GLY161 |
| A | ASP162 |
| A | GLY165 |
| A | PHE167 |
| A | ASP168 |
| A | PRO198 |
| A | PHE199 |
| A | LYS202 |
| A | HOH2117 |
| A | HOH2136 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 5 |
| Details | Binding site: {"evidences":[{"source":"PDB","id":"3ZY2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3ZY3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3ZY5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3ZY6","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"21966509","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3ZY2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3ZY3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3ZY5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3ZY6","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
