3ZY3
Crystal structure of POFUT1 in complex with GDP (crystal-form-III)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005783 | cellular_component | endoplasmic reticulum |
| A | 0006004 | biological_process | fucose metabolic process |
| A | 0006486 | biological_process | obsolete protein glycosylation |
| A | 0007219 | biological_process | Notch signaling pathway |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016757 | molecular_function | glycosyltransferase activity |
| A | 0036066 | biological_process | protein O-linked glycosylation via fucose |
| A | 0046922 | molecular_function | peptide-O-fucosyltransferase activity |
| B | 0005783 | cellular_component | endoplasmic reticulum |
| B | 0006004 | biological_process | fucose metabolic process |
| B | 0006486 | biological_process | obsolete protein glycosylation |
| B | 0007219 | biological_process | Notch signaling pathway |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016757 | molecular_function | glycosyltransferase activity |
| B | 0036066 | biological_process | protein O-linked glycosylation via fucose |
| B | 0046922 | molecular_function | peptide-O-fucosyltransferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1382 |
| Chain | Residue |
| A | MET172 |
| A | GLY173 |
| A | SER174 |
| A | ARG175 |
| A | LYS176 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1383 |
| Chain | Residue |
| A | SER284 |
| A | LYS285 |
| A | HOH2141 |
| A | HOH2142 |
| site_id | AC3 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE GDP A 1384 |
| Chain | Residue |
| A | ARG40 |
| A | PHE41 |
| A | GLY42 |
| A | ASN43 |
| A | HIS238 |
| A | ARG240 |
| A | ALA307 |
| A | SER308 |
| A | ASP309 |
| A | ASP334 |
| A | MET336 |
| A | SER355 |
| A | THR356 |
| A | PHE357 |
| A | HOH2014 |
| A | HOH2017 |
| A | HOH2018 |
| A | HOH2183 |
| A | HOH2189 |
| site_id | AC4 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1385 |
| Chain | Residue |
| A | LYS310 |
| A | ASP311 |
| A | HIS312 |
| A | MET313 |
| A | ILE314 |
| A | ARG330 |
| A | HOH2162 |
| A | HOH2172 |
| A | HOH2190 |
| site_id | AC5 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE GDP B 1381 |
| Chain | Residue |
| B | ARG40 |
| B | PHE41 |
| B | GLY42 |
| B | ASN43 |
| B | HIS238 |
| B | ARG240 |
| B | TRP245 |
| B | ALA307 |
| B | SER308 |
| B | ASP309 |
| B | ASP334 |
| B | MET336 |
| B | SER355 |
| B | THR356 |
| B | PHE357 |
| B | HOH2007 |
| B | HOH2008 |
| B | HOH2009 |
| B | HOH2010 |
| B | HOH2121 |
| B | HOH2122 |
| B | HOH2128 |
| B | HOH2129 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 10 |
| Details | Binding site: {"evidences":[{"source":"PDB","id":"3ZY2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3ZY3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3ZY5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3ZY6","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"21966509","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3ZY2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3ZY3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3ZY5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3ZY6","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
