3ZTP

Orthorhombic crystal form P21212 of the Aquifex aeolicus nucleoside diphosphate kinase

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004550	molecular_function	nucleoside diphosphate kinase activity
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0006183	biological_process	GTP biosynthetic process
A	0006228	biological_process	UTP biosynthetic process
A	0006241	biological_process	CTP biosynthetic process
A	0009142	biological_process	nucleoside triphosphate biosynthetic process
C	0004550	molecular_function	nucleoside diphosphate kinase activity
C	0005524	molecular_function	ATP binding
C	0005737	cellular_component	cytoplasm
C	0006183	biological_process	GTP biosynthetic process
C	0006228	biological_process	UTP biosynthetic process
C	0006241	biological_process	CTP biosynthetic process
C	0009142	biological_process	nucleoside triphosphate biosynthetic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	9
Details	BINDING SITE FOR RESIDUE GOL A 500

Chain	Residue
A	PHE50
A	TYR51
A	TYR52
A	VAL53
A	HIS54
A	SER127
A	GLU131
A	HOH2115
A	HOH2190

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site_id	AC2
Number of Residues	9
Details	BINDING SITE FOR RESIDUE SO4 A 510

Chain	Residue
A	LYS11
A	TYR51
A	ARG107
A	HIS120
A	HOH2029
A	HOH2114
A	HOH2115
A	HOH2156
A	HOH2191

---

site_id	AC3
Number of Residues	8
Details	BINDING SITE FOR RESIDUE SO4 C 510

Chain	Residue
C	LYS11
C	TYR51
C	LEU63
C	HIS120
C	HOH2021
C	HOH2139
C	HOH2150
C	HOH2165

---

Functional Information from PROSITE/UniProt

site_id	PS00469
Number of Residues	9
Details	NDPK Nucleoside diphosphate kinase (NDPK) active site signature. NaiHASDSP

Chain	Residue	Details
A	ASN117-PRO125

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Active site: {"description":"Pros-phosphohistidine intermediate","evidences":[{"source":"HAMAP-Rule","id":"MF_00451","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00451","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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