3ZML
Anopheles funestus glutathione-s-transferase epsilon 2 (GSTe2) protein structure from different alelles: A single amino acid change confers high level of DDT resistance and cross resistance to permethrin in a major malaria vector in Africa
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0003824 | molecular_function | catalytic activity |
A | 0004364 | molecular_function | glutathione transferase activity |
A | 0006749 | biological_process | glutathione metabolic process |
A | 0016740 | molecular_function | transferase activity |
B | 0003824 | molecular_function | catalytic activity |
B | 0004364 | molecular_function | glutathione transferase activity |
B | 0006749 | biological_process | glutathione metabolic process |
B | 0016740 | molecular_function | transferase activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 21 |
Details | BINDING SITE FOR RESIDUE GSH A 1222 |
Chain | Residue |
A | SER12 |
A | SER68 |
A | HIS69 |
A | PHE108 |
A | ARG112 |
A | HOH2102 |
A | HOH2114 |
A | HOH2187 |
A | HOH2310 |
A | HOH2311 |
A | HOH2312 |
A | PRO14 |
A | HOH2313 |
A | HOH2314 |
A | LEU36 |
A | HIS41 |
A | HIS53 |
A | THR54 |
A | ILE55 |
A | PRO56 |
A | GLU67 |
site_id | AC2 |
Number of Residues | 21 |
Details | BINDING SITE FOR RESIDUE GSH B 1222 |
Chain | Residue |
A | HOH2174 |
B | SER12 |
B | PRO14 |
B | LEU36 |
B | HIS41 |
B | HIS53 |
B | THR54 |
B | ILE55 |
B | PRO56 |
B | GLU67 |
B | SER68 |
B | HIS69 |
B | PHE108 |
B | ARG112 |
B | HOH2082 |
B | HOH2090 |
B | HOH2146 |
B | HOH2257 |
B | HOH2258 |
B | HOH2260 |
B | HOH2261 |