3ZML
Anopheles funestus glutathione-s-transferase epsilon 2 (GSTe2) protein structure from different alelles: A single amino acid change confers high level of DDT resistance and cross resistance to permethrin in a major malaria vector in Africa
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004364 | molecular_function | glutathione transferase activity |
| A | 0006749 | biological_process | glutathione metabolic process |
| A | 0016740 | molecular_function | transferase activity |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0004364 | molecular_function | glutathione transferase activity |
| B | 0006749 | biological_process | glutathione metabolic process |
| B | 0016740 | molecular_function | transferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE GSH A 1222 |
| Chain | Residue |
| A | SER12 |
| A | SER68 |
| A | HIS69 |
| A | PHE108 |
| A | ARG112 |
| A | HOH2102 |
| A | HOH2114 |
| A | HOH2187 |
| A | HOH2310 |
| A | HOH2311 |
| A | HOH2312 |
| A | PRO14 |
| A | HOH2313 |
| A | HOH2314 |
| A | LEU36 |
| A | HIS41 |
| A | HIS53 |
| A | THR54 |
| A | ILE55 |
| A | PRO56 |
| A | GLU67 |
| site_id | AC2 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE GSH B 1222 |
| Chain | Residue |
| A | HOH2174 |
| B | SER12 |
| B | PRO14 |
| B | LEU36 |
| B | HIS41 |
| B | HIS53 |
| B | THR54 |
| B | ILE55 |
| B | PRO56 |
| B | GLU67 |
| B | SER68 |
| B | HIS69 |
| B | PHE108 |
| B | ARG112 |
| B | HOH2082 |
| B | HOH2090 |
| B | HOH2146 |
| B | HOH2257 |
| B | HOH2258 |
| B | HOH2260 |
| B | HOH2261 |
