3ZLM

Fic protein from Neisseria meningitidis mutant E186G in complex with AMPPNP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0005524	molecular_function	ATP binding
A	0016740	molecular_function	transferase activity
A	0016779	molecular_function	nucleotidyltransferase activity
A	0018117	biological_process	protein adenylylation
A	0042803	molecular_function	protein homodimerization activity
A	0051302	biological_process	regulation of cell division
A	0070733	molecular_function	AMPylase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	16
Details	BINDING SITE FOR RESIDUE ANP A 300

Chain	Residue
A	LYS67
A	GLU148
A	SER182
A	TYR185
A	GLY186
A	MG301
A	HOH2085
A	HOH2115
A	ASN104
A	HIS107
A	GLY112
A	ASN113
A	GLY114
A	ARG115
A	ARG118
A	MET147

---

site_id	AC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG A 301

Chain	Residue
A	ANP300

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	125
Details	Domain: {"description":"Fido","evidences":[{"source":"PROSITE-ProRule","id":"PRU00791","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	5
Details	Motif: {"description":"Inhibitory (S/T)XXXE(G/N) motif"}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	14
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22266942","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	1
Details	Modified residue: {"description":"O-AMP-tyrosine; in vitro","evidences":[{"source":"PubMed","id":"22266942","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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