3ZJD

A20 OTU domain in reduced, active state at 1.87 A resolution

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016567	biological_process	protein ubiquitination
A	0016579	biological_process	protein deubiquitination
B	0016567	biological_process	protein ubiquitination
B	0016579	biological_process	protein deubiquitination

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL B 1358

Chain	Residue
B	CYS86
B	ARG87
B	ARG278
B	HOH2039

---

site_id	AC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL B 1359

Chain	Residue
A	GLU311
B	GLY281
B	TRP317

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL B 1360

Chain	Residue
B	ASP318
B	HIS323
A	MET308
B	TRP317

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL A 1357

Chain	Residue
A	GLY230
A	GLY231
A	LYS287
A	HOH2098

---

site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL B 1361

Chain	Residue
B	ARG45
B	CYS243
B	TYR244
B	HOH2016

---

site_id	AC6
Number of Residues	8
Details	BINDING SITE FOR RESIDUE EDO A 1358

Chain	Residue
A	LEU275
A	ASP285
A	LEU286
A	LYS299
A	GLU300
A	LEU303
A	ASN326
A	HOH2119

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Region: {"description":"Interaction with ubiquitin","evidences":[{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	Active site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	Active site: {"description":"Nucleophile","evidences":[{"source":"PubMed","id":"18164316","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Active site: {"description":"Proton acceptor","evidences":[{"source":"PubMed","id":"18164316","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---