3ZIU
Crystal structure of Mycoplasma mobile Leucyl-tRNA Synthetase with Leu-AMS in the active site
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004812 | molecular_function | aminoacyl-tRNA ligase activity |
| A | 0004823 | molecular_function | leucine-tRNA ligase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005829 | cellular_component | cytosol |
| A | 0006412 | biological_process | translation |
| A | 0006418 | biological_process | tRNA aminoacylation for protein translation |
| A | 0006429 | biological_process | leucyl-tRNA aminoacylation |
| A | 0016874 | molecular_function | ligase activity |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004812 | molecular_function | aminoacyl-tRNA ligase activity |
| B | 0004823 | molecular_function | leucine-tRNA ligase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005829 | cellular_component | cytosol |
| B | 0006412 | biological_process | translation |
| B | 0006418 | biological_process | tRNA aminoacylation for protein translation |
| B | 0006429 | biological_process | leucyl-tRNA aminoacylation |
| B | 0016874 | molecular_function | ligase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 26 |
| Details | BINDING SITE FOR RESIDUE LSS B 1576 |
| Chain | Residue |
| B | MET43 |
| B | ASP84 |
| B | TYR327 |
| B | TYR361 |
| B | GLY363 |
| B | GLY364 |
| B | GLU366 |
| B | HIS367 |
| B | HIS371 |
| B | GLN400 |
| B | MET402 |
| B | PHE44 |
| B | ILE403 |
| B | MET411 |
| B | HOH2064 |
| B | HOH2074 |
| B | HOH2077 |
| B | HOH2354 |
| B | HOH2371 |
| B | PRO45 |
| B | TYR46 |
| B | HIS53 |
| B | GLY55 |
| B | HIS56 |
| B | GLU58 |
| B | TYR60 |
| site_id | AC2 |
| Number of Residues | 26 |
| Details | BINDING SITE FOR RESIDUE LSS A 1638 |
| Chain | Residue |
| A | MET43 |
| A | PHE44 |
| A | PRO45 |
| A | TYR46 |
| A | HIS53 |
| A | GLY55 |
| A | HIS56 |
| A | GLU58 |
| A | ASP84 |
| A | TYR327 |
| A | TYR361 |
| A | GLY363 |
| A | GLY364 |
| A | GLU366 |
| A | HIS367 |
| A | HIS371 |
| A | GLN400 |
| A | MET402 |
| A | ILE403 |
| A | MET411 |
| A | HOH2075 |
| A | HOH2087 |
| A | HOH2090 |
| A | HOH2091 |
| A | HOH2385 |
| A | HOH2524 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL B 1577 |
| Chain | Residue |
| B | LYS70 |
| B | LYS396 |
| B | GLU503 |
| B | HOH2348 |
| site_id | AC4 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GOL A 1639 |
| Chain | Residue |
| A | TRP162 |
| A | LYS195 |
| A | MET197 |
| A | GLY289 |
| A | THR290 |
| A | GLY291 |
| A | GLU473 |
| A | ASP474 |
| A | HOH2210 |
| site_id | AC5 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GOL B 1578 |
| Chain | Residue |
| B | TRP162 |
| B | LYS195 |
| B | MET197 |
| B | GLY289 |
| B | THR290 |
| B | GLU473 |
| B | ASP474 |
| B | HOH2199 |
| B | HOH2487 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL A 1640 |
| Chain | Residue |
| A | LYS70 |
| A | LYS396 |
| A | GLU503 |
| A | HOH2375 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL B 1579 |
| Chain | Residue |
| B | GLU275 |
| B | LEU276 |
| B | VAL277 |
| B | GLU278 |
| B | ARG313 |
| B | HOH2294 |
| B | HOH2296 |
| site_id | AC8 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GOL A 1641 |
| Chain | Residue |
| A | GLU275 |
| A | LEU276 |
| A | VAL277 |
| A | GLU278 |
| A | TYR304 |
| A | ARG313 |
| A | HOH2321 |
| A | HOH2323 |
| A | HOH2350 |
| site_id | AC9 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GOL A 1642 |
| Chain | Residue |
| A | PRO319 |
| A | GLN320 |
| A | HOH2119 |
| A | HOH2223 |
| A | LEU88 |
| A | LEU170 |
| A | GLU174 |
| A | GLU186 |
| A | ARG252 |
| site_id | BC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL B 1580 |
| Chain | Residue |
| B | LEU88 |
| B | LEU170 |
| B | GLU174 |
| B | ARG252 |
| B | GLN320 |
| B | HOH2100 |
| B | HOH2214 |
| site_id | BC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 1643 |
| Chain | Residue |
| A | GLN102 |
| A | THR132 |
| A | PRO134 |
| A | TYR137 |
| A | TRP256 |
| A | HOH2136 |
| site_id | BC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL B 1581 |
| Chain | Residue |
| B | GLN102 |
| B | THR132 |
| B | PRO134 |
| B | TYR137 |
| B | TRP256 |
| B | HOH2120 |
| B | HOH2122 |
| B | HOH2488 |
