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3ZF5

Phage dUTPases control transfer of virulence genes by a proto-oncogenic G protein-like mechanism. (Staphylococcus bacteriophage 80alpha dUTPase Y84F mutant with dUpNHpp).

Functional Information from GO Data
ChainGOidnamespacecontents
A0000287molecular_functionmagnesium ion binding
A0004170molecular_functiondUTP diphosphatase activity
A0006226biological_processdUMP biosynthetic process
A0016787molecular_functionhydrolase activity
A0046081biological_processdUTP catabolic process
A0046872molecular_functionmetal ion binding
Functional Information from PDB Data
site_idAC1
Number of Residues22
DetailsBINDING SITE FOR RESIDUE DUP A 777
ChainResidue
AASN20
ALEU88
AGLY89
AGLN137
AARG160
AGLY164
APHE165
AGLY166
ASER167
ASER168
AMG1173
AARG64
AHOH2009
AHOH2017
AHOH2033
ASER65
AGLY66
AGLY78
ALYS79
AILE80
AASP81
APHE84

site_idAC2
Number of Residues4
DetailsBINDING SITE FOR RESIDUE MG A 1173
ChainResidue
AASP28
AARG64
ADUP777
AHOH2033

site_idAC3
Number of Residues3
DetailsBINDING SITE FOR RESIDUE NI A 1171
ChainResidue
AHIS72
AHIS96
AARG107

site_idAC4
Number of Residues6
DetailsBINDING SITE FOR RESIDUE NI A 1172
ChainResidue
AASP95
AASP95
AASP95
AHOH2018
AHOH2018
AHOH2018

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PDB entries from 2024-06-12

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