3ZF5
Phage dUTPases control transfer of virulence genes by a proto-oncogenic G protein-like mechanism. (Staphylococcus bacteriophage 80alpha dUTPase Y84F mutant with dUpNHpp).
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0004170 | molecular_function | dUTP diphosphatase activity |
| A | 0006226 | biological_process | dUMP biosynthetic process |
| A | 0009117 | biological_process | nucleotide metabolic process |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0046081 | biological_process | dUTP catabolic process |
| A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE DUP A 777 |
| Chain | Residue |
| A | ASN20 |
| A | LEU88 |
| A | GLY89 |
| A | GLN137 |
| A | ARG160 |
| A | GLY164 |
| A | PHE165 |
| A | GLY166 |
| A | SER167 |
| A | SER168 |
| A | MG1173 |
| A | ARG64 |
| A | HOH2009 |
| A | HOH2017 |
| A | HOH2033 |
| A | SER65 |
| A | GLY66 |
| A | GLY78 |
| A | LYS79 |
| A | ILE80 |
| A | ASP81 |
| A | PHE84 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG A 1173 |
| Chain | Residue |
| A | ASP28 |
| A | ARG64 |
| A | DUP777 |
| A | HOH2033 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE NI A 1171 |
| Chain | Residue |
| A | HIS72 |
| A | HIS96 |
| A | ARG107 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NI A 1172 |
| Chain | Residue |
| A | ASP95 |
| A | ASP95 |
| A | ASP95 |
| A | HOH2018 |
| A | HOH2018 |
| A | HOH2018 |
