Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0004713 | molecular_function | protein tyrosine kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006468 | biological_process | protein phosphorylation |
| B | 0004672 | molecular_function | protein kinase activity |
| B | 0004713 | molecular_function | protein tyrosine kinase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006468 | biological_process | protein phosphorylation |
| C | 0004672 | molecular_function | protein kinase activity |
| C | 0004713 | molecular_function | protein tyrosine kinase activity |
| C | 0005524 | molecular_function | ATP binding |
| C | 0006468 | biological_process | protein phosphorylation |
| D | 0004672 | molecular_function | protein kinase activity |
| D | 0004713 | molecular_function | protein tyrosine kinase activity |
| D | 0005524 | molecular_function | ATP binding |
| D | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE 1NX A 2099 |
| Chain | Residue |
| A | LEU828 |
| A | ASN954 |
| A | LEU956 |
| A | ASP967 |
| A | HOH2025 |
| A | GLY829 |
| A | LYS830 |
| A | VAL836 |
| A | ALA853 |
| A | GLU903 |
| A | TYR904 |
| A | LEU905 |
| A | GLY908 |
| site_id | AC2 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE 1NX B 2101 |
| Chain | Residue |
| B | GLN827 |
| B | LEU828 |
| B | ALA853 |
| B | MET902 |
| B | GLU903 |
| B | TYR904 |
| B | LEU905 |
| B | GLY908 |
| B | CYS909 |
| B | ARG953 |
| B | LEU956 |
| B | HOH2030 |
| C | ARG916 |
| site_id | AC3 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE 1NX C 2101 |
| Chain | Residue |
| B | ARG916 |
| C | GLN827 |
| C | LEU828 |
| C | VAL836 |
| C | ALA853 |
| C | MET902 |
| C | GLU903 |
| C | TYR904 |
| C | LEU905 |
| C | GLY908 |
| C | CYS909 |
| C | ASN954 |
| C | LEU956 |
| C | ASP967 |
| C | HOH2023 |
| C | HOH2073 |
| site_id | AC4 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE 1NX D 2100 |
| Chain | Residue |
| D | LEU828 |
| D | GLY829 |
| D | LYS830 |
| D | VAL836 |
| D | ALA853 |
| D | GLU903 |
| D | TYR904 |
| D | LEU905 |
| D | CYS909 |
| D | ASN954 |
| D | LEU956 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GOL C 2102 |
| Chain | Residue |
| B | ARG920 |
| C | GLU837 |
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 28 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGKGNFGSVElCrydplgdntgal......VAVK |
| Chain | Residue | Details |
| A | LEU828-LYS855 | |
| site_id | PS00109 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_TYR Tyrosine protein kinases specific active-site signature. CVHrDLAARNILV |
| Chain | Residue | Details |
| A | CYS945-VAL957 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"},{"source":"PROSITE-ProRule","id":"PRU10028","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 20 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 8 |
| Details | Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"18250158","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 6 |
| Details | Modified residue: {"description":"Phosphotyrosine; by autocatalysis","evidences":[{"source":"PubMed","id":"15831699","evidenceCode":"ECO:0000269"}]} |
