3ZEF
Crystal structure of Prp8:Aar2 complex: second crystal form at 3.1 Angstrom resolution
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000244 | biological_process | spliceosomal tri-snRNP complex assembly |
| A | 0000387 | biological_process | spliceosomal snRNP assembly |
| A | 0003674 | molecular_function | molecular_function |
| A | 0005515 | molecular_function | protein binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005682 | cellular_component | U5 snRNP |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006397 | biological_process | mRNA processing |
| A | 0008380 | biological_process | RNA splicing |
| B | 0000398 | biological_process | mRNA splicing, via spliceosome |
| B | 0003723 | molecular_function | RNA binding |
| B | 0005681 | cellular_component | spliceosomal complex |
| B | 0008233 | molecular_function | peptidase activity |
| B | 0008237 | molecular_function | metallopeptidase activity |
| B | 0017070 | molecular_function | U6 snRNA binding |
| B | 0030623 | molecular_function | U5 snRNA binding |
| D | 0000244 | biological_process | spliceosomal tri-snRNP complex assembly |
| D | 0000387 | biological_process | spliceosomal snRNP assembly |
| D | 0003674 | molecular_function | molecular_function |
| D | 0005515 | molecular_function | protein binding |
| D | 0005634 | cellular_component | nucleus |
| D | 0005682 | cellular_component | U5 snRNP |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0006397 | biological_process | mRNA processing |
| D | 0008380 | biological_process | RNA splicing |
| E | 0000398 | biological_process | mRNA splicing, via spliceosome |
| E | 0003723 | molecular_function | RNA binding |
| E | 0005681 | cellular_component | spliceosomal complex |
| E | 0008233 | molecular_function | peptidase activity |
| E | 0008237 | molecular_function | metallopeptidase activity |
| E | 0017070 | molecular_function | U6 snRNA binding |
| E | 0030623 | molecular_function | U5 snRNA binding |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 42 |
| Details | Region: {"description":"Leucine-zipper"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"21764848","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"21764848","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"21764848","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 258 |
| Details | Domain: {"description":"MPN","evidences":[{"source":"PROSITE-ProRule","id":"PRU01182","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 171 |
| Details | Region: {"description":"Restriction endonuclease homology domain"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 253 |
| Details | Region: {"description":"RNase H homology domain"} |
| Chain | Residue | Details |
